The name of the coronavirus mutation in South Africa sounds awkward: E484K - because of a change in gluatamate (E) and lysine (K) at prickly protein location 484. But the name is appearing more and more frequently and is becoming increasingly important. Scientists fear that vaccines could be less effective against virus forms with this mutation. It is found in the highly contagious variants that are rampant in South Africa and Brazil - an important difference from the variant in England, against which the Pfizer / Biontech vaccine has been reported to be largely effective.