US plans to study why Pfizer vaccine can make some people allergic
Science and Technology Daily, Beijing, December 22 (Reporter Liu Xia) According to a report on the US Consumer News and Business Channel website on the 21st, officials from the National Institute of Allergy and Infectious Diseases (NIAID) stated that the United States is planning to launch a new study to clarify Why a small number of people have severe allergic reactions shortly after being injected with the new crown vaccine (hereinafter referred to as Pfizer vaccine) developed by Pfizer and German Biotech.
NIAID Allergy, Asthma and Respiratory Biology Director Alkis Togias said that the study is still in the early planning stages and will recruit hundreds of people with a history of severe allergic reactions.
His department will lead the research, and they hope the research will begin within a few weeks.
Although people vaccinated by Pfizer have reported this allergic reaction, this study may also focus on the vaccine developed by Modena.
It was previously reported that a small number of people had allergic reactions to Pfizer's vaccine. Last week, a clinician in Alaska developed allergic symptoms 10 minutes after injecting Pfizer vaccine, becoming the third medical worker in the state to have an adverse reaction to the vaccine. .
Togias said: "We are a little worried that those with allergies may not dare to get vaccinated now."
Moncef Sloy, the head of the U.S. Covid-19 vaccine project, mentioned this research at a briefing on Operation Warp Speed held earlier on Monday.
He said: "We are advancing a plan to test the vaccine developed by Modena (hereinafter referred to as the Modena vaccine) and Pfizer vaccine on subjects who are extremely allergic, and are trying to understand the immune mechanism behind this allergic reaction. ."
Medical experts say that allergic reactions caused by vaccines are rare, but sometimes they occur.
The U.S. Food and Drug Administration (FDA) said last Thursday that they are investigating allergic reactions after the Pfizer vaccine.
The core of Pfizer vaccine and Modena vaccine are messenger ribonucleic acid (mRNA), which is composed of about 2,000 biochemical genes, which transmits instructions to the immune system of the vaccinated to recognize and fight the new coronavirus infection.
US health officials say these vaccines are relatively safe, with only 10% to 15% of subjects reporting in clinical trials that side effects are "obvious."
According to the US Food and Drug Administration, the most common side effects of the Modena vaccine are fatigue, headache, and muscle pain, as well as rare symptoms such as nausea, vomiting, and facial swelling, which may be caused by injections.
Some side effects are difficult to eliminate, but most of them will go away on their own within a week.
Togias said that this study may also recruit some people who have not had an allergic reaction for comparison. In addition, before the start of the study, they must also propose a very detailed plan, which needs to be reviewed and approved by the ethics committee after it is approved by the FDA.