China News Service, October 24 (Reporter Chen Jing) Phenotypics is another strategic commanding height and original source of innovation in life sciences after genomes.

China has taken the lead in laying out the large scientific plan of the human phenotype group in the world.

  The reporter was informed on the 24th that since 2018, there have been more than 100 basic and applied demonstration studies of the human phenotype, which have been carried out simultaneously with the support of the major special project of the "International Human Phenotype Project (Phase I)". Some projects have been achieved. "Early Harvest".

Projects related to the development of original innovative drugs based on human phenotypic methods are also being actively promoted.

  The 2nd China Human Phenotype Group Conference and the 3rd International Human Phenotype Group Symposium opened on the 24th.

As the most important cutting-edge academic summit in the field of phenotyping research, both conferences this year focused on the theme of "Human Health in the Phenotypic Era", attracting more than 300 official representatives and nearly 1,000 listeners from around the world to participate online and discuss together Scientific and technological solutions to major human health issues.

In the three days from now, 20 top scholars and experts from 9 countries including Germany, the United Kingdom, Japan, the United States and China will share cutting-edge innovations and latest achievements in this field.

  Phenotype is the biological characteristic of a living body.

Phenotype group refers to the collection of all phenotypes in the whole process of organisms from microscopic composition to macroscopic, from embryonic development to senescence and death.

Genes and environment together determine the phenotype.

Although the concept of the "Human Phenotype Group Project" was first proposed by American scientists, China took the lead in laying out the Human Phenotype Group Science Program on a global scale and substantively promoting related research.

Since 2018, China has built a basic framework of "four in one" in terms of platform construction, data systems, collaborative networks, and scientific research.

  China is committed to building two international and domestic collaborative innovation networks. Since 2018, it has established a "Chinese Human Phenotyping Group" consisting of more than 60 domestic first-class universities, scientific research institutions, tertiary hospitals and leading enterprises, including 23 academicians of the two academies. Research Collaboration Group (HPCC)”; At the same time, the “International Human Phenotype Group Research Collaboration Group (IHPC) including 22 high-level scientific research institutions from 17 countries including the United States, Britain and Germany and 10 academicians from various countries was established. ".

  In the two conferences held from the same day, three co-sponsors of the "International Human Phenotype Group Research Collaboration Group" will serve as co-chairs of the international seminars.

The three co-sponsors include Nicholson, director of the Australian National Phenotyping Research Center, Hood, a foreign academician of the Chinese Academy of Sciences, and Jin Li, an academician of the Chinese Academy of Sciences.

Wu Yuanbin, director of the Department of Social Development and Science and Technology of the Ministry of Science and Technology, attended the opening ceremony of the 2nd China Human Phenotype Group Conference and delivered a speech.

At the opening ceremony, a number of experts gave keynote speeches on the human microbiome, pathological phenotypes and phenotypes of diseases, and TCM diagnosis and treatment.

  It is understood that in 2015, Fudan University undertook the National Science and Technology Fundamental Work Special Project "Survey on Phenotypic Characteristics of Physical Anthropology of Various Ethnic Groups in China", collecting morphological observations of more than 40,000 people from 55 ethnic groups, and nearly 1,000 human functions In March 2018, Shanghai’s first major municipal science and technology project "Human Phenotype Group Plan (Phase I)" was officially launched; the 2018 Human Phenotype Group Plan The basic framework of a collaborative innovation network at home and abroad is formed; in 2019, the Shanghai International Human Phenotypic Research Institute was established.

  "The human phenotype project is to conduct full-scale, full-cycle, micro-to-macro, precise systematic measurement of various human phenotypes, so as to further understand the relationship between various human phenotypes and human health." Jin Li told reporters.

He introduced that the research results of the human phenotype group can help people improve the accuracy and efficiency of medical diagnosis by a whole scale, realize the precise classification and classification of diseases, guide the clinical realization of precise diagnosis and personalized treatment, and promote the precise health management of individuals. .

  Jinli pointed out that this is of great significance to support precision medicine and promote human health.

The Human Phenotype Group Project and related scientific research results will discover a batch of brand-new phenotypic markers, obtain a large number of new drug targets and new mechanisms, and provide super engines for new diagnostic reagents and products, smart medical devices and equipment.

Jinli pointed out that the in-depth advancement of the human phenotype program will ultimately provide China with a lasting innovation drive to lead the reform of the biomedical industry.

(Finish)