China News Service, Lanzhou, September 21 (Reporter Nan Ru Zhuoma) "In the face of the new crown epidemic, the biomedicine and life and health technology industries have become anti-epidemic weapons. This epidemic has also prompted countries and all walks of life to re-examine the status and status of the medical and health industry. Value." Rui Guozhong, vice chairman of the China Technology Entrepreneurship Association and secretary general of the Biomedical Park Development Alliance, said in Lanzhou that in the post-epidemic era, the biomedical industry has ushered in a new development trend.

  From September 19th to 20th, the 2020 4th China Biomedical Park Industry Innovation and Development Conference and the 3rd Lanzhou Independent Innovation Forum will be specifically undertaken by the Lanzhou High-tech Zone Management Committee.

The conference focused on the needs of major national biological and health strategies, and set up academician expert keynote reports, China Biomedicine Innovation Drive and High-quality Development Summit, innovative and entrepreneurial project roadshows and other activities to discuss innovative medicines, innovative Chinese medicines, cell gene therapy, new vaccines, in vitro Frontier technologies and industrial developments such as diagnosis, brain imaging, and radiology.

  Nearly a hundred industrial parks, pharmaceutical companies, colleges and universities, investment institutions, innovation and entrepreneurship service organizations, industry experts, corporate elites and other pharmaceutical experts from across the country gather, and there is also the 2013 Nobel Prize in Physiology or Medicine, Randy. Shekman and other international medical experts participated in the "Cloud Conference" through the Internet and shared the latest research progress of his team in the medical field.

The Biomedical Park Industry Innovation and Development Conference is one of the main forums of the Lanzhou Science and Technology Expo.

Photo by Yin Chunyong

The cluster effect of biomedical innovation industry is beginning to show

  Zhang Mu, deputy director of the Torch Center of the Ministry of Science and Technology, disclosed that the total industrial output value of the 169 national high-tech zone biomedical companies reached 1.8 trillion yuan, and their operating income exceeded 2 trillion yuan, accounting for 8.1% and 5.8% of the national high-tech zone's total economy. .

The total number of biopharmaceutical companies included in the statistics in the National High-tech Zone totaled 919.2 billion yuan, of which 576.0 billion were high-tech enterprises and 219.2 billion yuan were those with revenues exceeding 100 million yuan.

  Zhang Mu said that currently, the biopharmaceutical industry focuses on national high-tech zones, and has deployed 25 biomedical innovative industrial clusters, accounting for nearly 1/4 of the total number of clusters. The biomedical industry cluster has strong R&D strength, large industrial scale and development potential. It is generally one of the pillar industries in the high-tech zone where it is located, and has become an important starting point for the transformation and upgrading of each high-tech zone to achieve high-quality development.

The Biomedical Park Industry Innovation and Development Conference aims to explore new trends, new changes, and new opportunities in the biomedical industry in the post-epidemic era.

Photo by Yin Chunyong

  Sun Yu, director of the Lanzhou High-tech Zone Management Committee, said that the biomedical industry is its first major industry, relying mainly on the advantages of Gansu biomedical resources, focusing on traditional Chinese medicine and natural medicine, chemical medicine, biological products, medical equipment, and tumor diagnosis and treatment. Direction, build a multi-level life science research innovation and achievement transformation system, promote the characteristic, large-scale and clustered development of the biomedical industry, gather more than 200 biomedical companies of various types, and achieve a total output value of 14.2 billion yuan in 2019.

  During the fight against the new crown pneumonia epidemic, enterprises in the Lanzhou High-tech Zone have successfully developed new crown virus detection kits and key products and achievements such as the inhibition of new crown virus intrusion into the human body by successfully developing new crown virus detection kits, which have contributed to the detection and treatment of new crown pneumonia. Lanzhou Power".

  Wei Gu, director of the Industrial Cluster Division of the Torch Center of the Ministry of Science and Technology, said that China’s existing clusters are generally developing well. The overall innovation capability of biomedical innovative industrial clusters is increasing, the industrial chain is relatively complete, and the development of new drugs is making rapid progress. Class clusters (parks) have occupied an important position.

However, there is still a lot of room for growth in biomedical innovative industrial clusters, and efforts must be made to overcome key core technologies and enhance industrial innovation capabilities.

Yuri Frievich Medaniko, director of the laboratory of the Institute of Thermophysics of the Russian Academy of Sciences and a doctor of technical science, gave an online speech.

Photo by Du Ping

Sharing cutting-edge medical technology and scientific research results

  The cause of Parkinson’s disease, intelligent targeted tumor gene therapy drug platform, peptide innovative drug development, diabetes and hemophilia innovative drug development, neutron capture therapy cancer system, flow chemistry, Chinese herbal medicine DNA barcode identification system...in two days , Participating experts and scholars, pharmaceutical companies, associations and other industry experts, shared achievements and suggestions on biomedical innovation.

  Xiao Guoqing, president of the Lanzhou Branch of the Chinese Academy of Sciences, made a report on the "Development and Application of Heavy Ion Therapy Technology", and disclosed that there are more than 4 million new cancer patients and more than 2 million deaths each year in China, and 80% of the patients are in the advanced stage when malignant tumors are discovered.

At present, Gansu has built 6 heavy ion cancer treatment devices. China has independently innovated and completed the overall software solution for heavy ion radiotherapy, breaking the international monopoly of high-end medical equipment, and successfully applied to the clinical treatment of the Wuwei demonstration device, and was put into commercial operation. This March Since receiving patients, 100 patients have been treated with obvious curative effect.

  "Currently, there are no effective western medicine preparations for fatty liver disease. We found from traditional Chinese herbal medicine that Scutellaria baicalensis Georgi can directly act on related proteins in fatty acid metabolism pathways. Further experiments have verified that Scutellaria baicalensis Georgi has a lipid-lowering effect." Chemistry and Molecular Engineering of Peking University Professor Wang Chu shared this information during his speech here.

  When Randy Shekman shared his and his team’s latest research progress, he said that he has found 20 gene loci that may cause Parkinson’s disease and hopes to start from these directions that may affect the development of neurons to clarify the disease. Cause.

"About 30% of Parkinson's disease suffers from dementia symptoms, which may be the result of the spread of Lewy bodies in the brain." He said that the achievement in the past ten years is the discovery of a genetic form of Parkinson's disease.

At the flow chemistry symposium, Jiang Yi, president of Corning Reactor Technology Co., Ltd., gave a report "Micro-channel continuous reaction technology to improve quality and reduce costs, and achieve safe production of drugs."

Photo by Zhang Jing

Experts and scholars hotly discuss "innovative Chinese medicine"

  "Tumors and metabolic diseases seriously endanger the safety of human life, and 90% of more than 4,500 diseases are incurable." Chen Shilin, director of the Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, said that social development and changes in the spectrum of diseases have brought about the development of Chinese medicine. Rigid demand.

  "The curative effect of traditional Chinese medicine has attracted worldwide attention. For example, artemisinin saves more than 14 million people from malaria every year." Yang Zhenzuo, Dean of the School of Chemistry and Molecular Engineering, Peking University, "Exploring the Frontiers of Green Synthesis and Manufacturing of Active Natural Products" In the keynote report of "Technology", he said frankly that my country is rich in important resources, but research on traditional Chinese medicine needs to be strengthened.

  Yang Zhen said that in the global TCM market of 30 billion U.S. dollars, South Korea, Japan, the United States, etc. directly monopolized about 90% of the international market, and China accounted for less than 5%, especially Japan and South Korea imported large quantities of rough processing from China. The raw materials of traditional Chinese medicine, after refined into Chinese patent medicine, occupy more than 80% of the global Chinese medicine market.

He believes that by carrying out research on the total synthesis of natural products with important biological functions, it is of great significance for accelerating the promotion of green processes such as microchannel reactions, breaking through core green technologies, cultivating high-quality innovative enterprises, and creating an innovation platform.

On August 28, 2020, the 3rd China (Gansu) Traditional Chinese Medicine Industry Expo opened in Longxi County, the "Millennium Medicine Township". Zhong Nanshan communicated on-site through online cloud video.

(Data Map) Photo by Zhang Jing

  Director Chen Shilin also stated that it is necessary to use scientific and technological means to promote the innovation and internationalization of traditional Chinese medicine, and to solve the chaotic phenomenon of Chinese herbal medicine varieties, in order to solve the bottleneck of Chinese patent medicine "going out".

He suggested the establishment of a national Chinese medicine gene database, a national platform for the breeding of high-quality medicinal materials, an integrated technology system for comprehensive prevention and control of high-quality medicinal materials diseases and pests, and the development of big data and artificial intelligence in Chinese medicine, the introduction of high-quality Chinese medicine quality improvement technical standards and specifications, and the creation of Chinese herbal medicine DNA barcode identification System to implement objective identification and increase investment in the modernization of Chinese medicine.

  Shi Liqiang, vice president of the Chinese Society for Drug Administration, said that under the guidance of the concept of "Healthy China" in the post-epidemic era, the whole society has paid more attention and capital support to the medical and health industry, and enhanced the industry by strengthening medical innovation and drug supervision. Development level, promote the healthy development of the pharmaceutical industry, and protect the safety and health of human life.

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