Realize the dream of having healthy children for families suffering from genetic diseases

Dubai Fertilization eliminates genetic diseases through genetic testing

• The center brought hope to an Emirati family who has lived for more than 15 years without children.

  From the source

• The center brought hope to an Emirati family who has lived for more than 15 years without children.

  From the source

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The director of the Dubai Fertility Center of the Dubai Health Authority, Hana Obaid Tawara, confirmed to "Emirates Today" that the center has succeeded in conducting specific fertilization procedures, using pre-implantation genetic testing technology, realizing the dream of families with genetic diseases to have healthy children. .

She stated that there are eight common factors between males and females that lead to delayed pregnancy and infertility.

In detail, Tawara said, “The center has brought hope and happiness to many Emirati families, including a family that had three children, two of whom suffer from delayed growth in the womb, and the third poor growth after childbirth, in addition to repeated miscarriages during pregnancy naturally.

Through the evaluation of the case at the center, and the conduct of genetic tests after the IVF technique, I had a fourth, healthy baby, with normal weight and growth.

She added that the center has also succeeded in achieving hope for an Emirati family, after living for more than 15 years, specifically since 2004, without children, as the couple suffered delayed pregnancy and childbearing naturally, and they traveled to many countries in search of solutions, during which they underwent 10 attempts at treatment with techniques. Fertilization inside and outside the country, before they decided to go to the center, where he was able to help them conceive two children through medical assistance techniques and genetic testing.

The family had their first child in April 2018, and their second child last June.

Tawara explained that the center is one of the leading specialized centers in the introduction of genetic detection examinations for genetic diseases in the field of fertilization services at the state level, as it started providing tests in 2013, with the aim of contributing to reducing the frequency of childbirths of unhealthy children who carry genetic diseases due to a history of Family friendly, reducing pregnancies that end in recurrent miscarriages.

She added that the center achieved a success rate of 67% through the use of genetic testing, while the total of the tests conducted during the period from 2013 until last June amounted to 1718 examinations, which brought many benefits, especially for families with genetic diseases and frequent miscarriages.

Tawara revealed that the 'Born in Hope' initiative, launched by His Highness Sheikh Mohammed bin Rashid Al Maktoum, Vice President and Prime Minister of the UAE and Ruler of Dubai in 2013, contributed to reducing the burden and financial cost on citizens, through treatment at the center, as the number of births reached 408 children have benefited from it, since its launch until the end of last year.

She explained that the eight common factors between men and women for delayed pregnancy and poor fertility are: genetic diseases in the family, chronic diseases, repeated implantation failure, recurrent miscarriage, the birth of abnormal children in the past, abnormal genotype, poor fertility after cancer treatment, and imbalances Hormonal.

And Tawara continued: “In addition to the previous factors, there are 10 main causes of infertility in men, which are: unexplained weakness in the quality and number of sperms, hypogonadism, obstruction of the reproductive tract, vasectomy after infection, infections of the genitourinary system, and absence Or a lack of sperm in the semen, poor semen analysis test results, high sperm DNA breakdown index, abnormal genotype, and systemic diseases - after chemotherapy.

With regard to women, 11 causes of delayed pregnancy and impaired fertility have been identified, namely: ovulation disorders - polycystic ovary syndrome, advanced age in the wife, endometriosis, pelvic adhesions, blockage of tubes, other problems in the tubes, decreased ovarian reserve or decreased ovarian response, Uterine abnormalities, uterine fibrosis, factors related to the cervix, vaginismus.

5 embryo examinations

The director of the Dubai Fertility Center, Hana Obaid Tahwara, said that the center provides five services for examining fetuses, which are:

Genetic examination of fetuses for the purpose of determining the sex of the fetus by examining the chromosomes before returning the embryos to the womb

A DNA test with BCR technology to diagnose a specific genetic disorder, such as thalassemia or sickle cell anemia.

- Examination of DNA with the technique of "MicroRay", a complete examination of chromosomes to detect changes in the number of chromosomal copies on a large and high-resolution genomic scale.

- DNA screening with next-generation sequencing technology (NGS), a technique for rapidly analyzing DNA and studying the entire genome or part of it.

- HLA, tissue conformance assay technique, by examining the conforming tissues with the "HAGLE-E" technology for genetic diagnosis of embryos before implantation for the purpose of diagnosing tissue-identical embryos.

408 children have benefited from the “Born in Hope” initiative since its launch.

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Factors that cause poor fertility in men and women.

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