China News Service, August 31 (Reporter Chen Jing) Lele, who just turned nine, was diagnosed with familial hypercholesterolemia when he was two years old. Liver transplantation is the only treatment, otherwise he may not survive 30 year old.

  The reporter learned on the 31st that the children's liver transplant team of Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine had undergone 4 hours of surgery on the night of Lele's 9th birthday, allowing him to get rid of the pain and torture and get a new life.

  Familial hypercholesterolemia is a rare genetic metabolic disease, due to congenital genetic defects caused by liver lipid metabolism defects, leading to severe hypercholesterolemia. This is the most serious type of lipid metabolism disease, which can lead to various life-threatening complications of cardiovascular disease.

  It is understood that the serum cholesterol concentration of patients is usually 6 to 8 times higher than normal people, and systemic severe atherosclerosis will gradually appear. Most of the children show symptoms of coronary heart disease around the age of 10.

  At 2 months of birth, his parents accidentally discovered that Lele had xanthomas on his limbs. They went to the hospital and found that the child's blood cholesterol and blood lipid levels were abnormally high. When he was 2 years old, genetic testing confirmed that he had familial hypercholesterolemia.

  In an interview, Wan Ping, an expert on pediatric genetic and metabolic diseases at Renji Hospital, told reporters that commonly used lipid-lowering drugs have little effect on such patients. If they do not receive liver transplantation, patients often die of cardiovascular disease before the age of 30. According to Professor Xia Qiang, director of liver surgery at Renji Hospital, although the disease is rare, it is extremely harmful.

  It is reported that the parents of the child carry the pathogenic gene of familial hypercholesterolemia and cannot donate the liver to the child. Lele can only register and wait for a suitable liver source. On the child's 9th birthday, the liver source appeared. That night, Lele underwent classic orthotopic liver transplantation.

  The hospital told reporters on the 31st that the child was awake in the intensive care unit on the second day after the operation and recovered well. (Finish)