(Fighting against New Coronary Pneumonia) The latest international case study found that the new coronavirus may spread through the placenta

  China News Service, Beijing, July 14 (Reporter Sun Zifa) Springer Nature's international academic journal "Nature-Communication" published a case study online on the 14th, saying that the relevant evidence proves that a new coronavirus (SARS-CoV -2) Mothers who test positive may pass the placenta and transmit the virus to the baby.

  The paper pointed out that past research has shown that the transmission of new coronavirus may occur during the perinatal period (before and after birth), but it is not clear whether this occurs through the placenta (a cervical route) or because of environmental exposure.

  Corresponding author of the paper, the results of a case study reported by Daniele DeLuca and colleagues at the University of Saclay University in Paris, France, show that the transmission of neocoronavirus through the placenta is possible: a pregnant woman in her twenties Fever and severe cough were admitted to the hospital. The blood test, nasopharyngeal swab and vaginal swab confirmed the existence of the new coronavirus "E" and "S" genes (encoding the viral envelope and spike protein, respectively). After 1 hour of caesarean section, they were collected The nasopharyngeal swab and rectal swab of the baby were collected, and then collected again after 3 days and 18 days, and the presence of "E" and "S" genes was detected. At the same time, neonatal blood and bronchoalveolar perfusion tests were also positive.

  They also observed that infants developed neurological symptoms related to the new coronavirus infection, and were similar to the symptoms reported by adult patients. Their neuroimaging analysis showed that the white matter was damaged. The researchers speculated that it might be caused by vascular inflammation induced by the new coronavirus infection. No other viral or bacterial infections were found, and all other neonatal diseases that may cause these clinical symptoms were excluded. After treatment, the mother and her child eventually recovered.

  The author and collaborators also measured that the viral load in the placenta is higher than in amniotic fluid and maternal blood, which means that the new coronavirus may actively replicate in placental cells and cause neonatal viremia. This is consistent with the level of inflammation found in the histological examination of the placenta. By confirming the presence of new coronavirus in placental tissue, maternal blood and neonatal blood, they concluded that mother-to-child transmission (of the new coronavirus) is most likely to occur through the placenta. (Finish)