China News Service, Guangzhou, June 23 (Cai Minjie, Li Hanzhao) Chest tightness, palpitations, dizziness... For 4 years, Mr. Zou of Jiangxi has been suffering from the torture and pain caused by dilated cardiomyopathy, and his heart has become the only one that saves his life. hope. The First Affiliated Hospital of Sun Yat-sen University said on the 23rd that under the rescue of the team of Wu Zhongkai, a professor of cardiac surgery in the hospital, Mr. Zou, a patient with end-stage heart disease, underwent heart transplantation with different blood types, and he is currently eating normally.
Mr. Zou, 41, is from Jiangxi Province. Four years ago, after a slight activity, Mr. Zou began to show palpitations and shortness of breath without cause. Upon examination by the doctor, he was diagnosed with dilated cardiomyopathy. Three months ago, he suffered frequent chest tightness, palpitations, and dizziness, which made him lie down and could not eat. Mr. Zou came to the First Affiliated Hospital of Sun Yat-sen University.
After a color Doppler ultrasound examination, it was found that Mr. Zou's left ventricle had expanded to 71 mm, and the left ventricular ejection fraction had dropped to 26%, while the left ventricle of a normal person was about 45 mm, and the heart ejection fraction was at least 50%. After hospitalization, although Mr. Zou had undergone anti-heart failure treatment, his condition was still getting worse, and an intra-aortic balloon counterpulsation device was applied on May 25.
On June 6, a 19-year-old donor was donated. Unlike usual, the blood type of the donor is type O, while the blood type of the recipient Mr. Zou is type A. Prior to this, heart transplant donors and recipients tried to choose the same blood type. If they continue to wait for donors with the same blood type, Mr. Zou is at high risk of death at any time.
After a general discussion, the expert team decided to use this blood type compatible O-type donor for heart transplant surgery. At 10 o'clock on June 7, Mr. Zou's pericardial cavity was opened. "The myocardium has become very thin, like a layer of paper. This kind of heart condition has reached the state where the lamp is dry." Wu Zhongkai introduced.
After obtaining the heart, the team of experts quickly transplanted it into Mr. Zou's body. With the anastomosis of the left atrium and the aorta completed, the aortic occlusion clamp was opened and blood flow rushed into the implanted "new" heart.
According to Wu Zhongkai, the entire transplantation procedure took only 4 hours, and the patient did not infusion of red blood cells, which is also rare in many conventional cardiac operations. "Zero" blood transfusion avoids the occurrence of many blood transfusion complications, reduces the risk of rejection and allergies, and shortens the postoperative recovery time of patients.
In recent years, with the development and use of new monoclonal anti-rejection drugs, in blood transplantation, allogeneic transplantation has successfully achieved breakthroughs, such as O-type kidney transplantation into A-type or B-type donors has been quite common in parental kidney transplantation .
"Heart transplantation does not allow room for fault tolerance." Wu Zhongkai said that in terms of heart transplantation, because it is an orthotopic organ transplantation, the risk of surgery is higher than that of kidney transplantation, and the surgical selection of xenotransplantation will be more strict. This time, the Zhongshan No. 1 Hospital undergoes allogeneic heart transplantation, which can provide a reference for similar patients to shorten the donor waiting time in the future. (Finish)