China News Agency, Shanghai, June 8 (Reporter Chen Jing) A reporter was informed on the 8th that Chinese medical experts have systematically analyzed and researched more than 2.21 million research subjects over two years and found that hypertension can increase the risk of cognitive impairment. This study is of great significance for identifying high-risk groups with cognitive impairment and formulating effective prevention strategies.
Dementia is an important global health challenge today, so far there is no effective strategy to reverse or cure dementia. Studies have shown that blood pressure is related to neuropathological changes in dementia. It is reported that the research results of Chinese scholars have been published in the latest issue of Hypertension, the top journal in the field of hypertension, which has aroused widespread concern in the international medical community.
In this study, the clinical research team of Professor Yu Jintai, Department of Neurology, Huashan Hospital Affiliated to Fudan University, combined with the team of Professor Tan Lan, Department of Neurology, Qingdao City Hospital, found that middle-aged hypertension can significantly increase the occurrence of cognitive impairment risk. Experts further found through dose response analysis that the risk of cognitive impairment increased significantly when the systolic blood pressure of middle-aged hypertensive patients exceeded 130 mmHg.
The researchers also found that high systolic blood pressure, low diastolic blood pressure, and abnormal blood pressure regulation in later years will increase the risk of cognitive impairment. Studies have shown that diastolic blood pressure is controlled at 90 to 100 mmHg in later years, and the most common dementia, Alzheimer's disease, has the lowest risk.
Yu Jintai's clinical research team further conducted a prospective study on antihypertensive drugs and dementia risk. The results found that the use of antihypertensive drugs not only reduces the risk of dementia in people with normal cognition, but also may reduce mild cognitive function. The risk of patients with disorders progressing to dementia.
Yu Jintai advocated that in order to prevent the occurrence of cognitive impairment, a multidimensional, comprehensive and personalized blood pressure management strategy should be established as soon as possible. (Finish)