China News Service, Beijing, April 2 (Reporter Sun Zifa) The international academic journal Nature has recently published a German medical expert's study of cases of new coronavirus (SARS-CoV-2) infection and found that the replication of new coronavirus in patients' upper respiratory tract More active, indicating that the virus may have a higher level of "detoxification" within the first week after symptoms appear.
On March 25th local time, in Hillersheim, Germany, staff and volunteers converted the city hall into a medical center for the treatment of patients with the new coronavirus. The picture shows the reconstruction site of the Hillersheim Treatment Center.
"Nature" provided a press release to the media on the 2nd. Corresponding authors of the results of the paper are Christian Drosten of Scherritt Medical School in Berlin, Germany and Clemens-Martin Wendtner of Schwabing Hospital in Munich. A detailed virological analysis of young patients with confirmed new coronavirus infection was performed with a detailed virological analysis. Patients' throat swabs and lung tissue specimens, sputum (mucus secreted from the respiratory tract), and stool, blood, and urine collected during their clinical course were investigated.
The authors found that patients had higher levels of viral replication in the upper respiratory tract tissues and higher levels of viral excretion in the upper respiratory tract within the first week after symptoms appeared. With the gradual reduction of symptoms, infectious strains could still be isolated from patients' throat swabs and lung tissue samples on the 8th day after the symptoms appeared. Two of these patients had early signs of pneumonia. High levels of virus excretion continued on day 10 or 11. After the symptoms disappeared, viral RNA was still detected in the sputum.
The authors point out that, in a comprehensive view, these preliminary results show that in the early stages of patients with relatively mild symptoms, the new crown virus has the strongest viral excretion capacity in the upper respiratory tract, and subsequent studies may help assess the viral load of patients one week after symptoms appear. Whether an increase in the amount may indicate an increase in symptoms. (Finish)