This was reported by the State Service for Emergency Situations of Ukraine.
"The fire continues to be liquidated at the Odessa College of Economics, Law and the hotel and restaurant business ... there is a threat of collapse of structures and the spread of fire," the service said on Facebook.
According to preliminary information, the fire occurred on the third floor of a six-story educational building.
Currently, 40 people have been evacuated from the institution.
In August, a fire broke out in the Odessa Hotel Tokyo-Star, killing nine people.