"We advise the United States not to stand its ground, otherwise China will have to take serious countermeasures, all responsibility for the consequences of which the United States will have to bear," RIA Novosti quoted the Chinese Foreign Ministry as saying.
The Chinese Foreign Ministry called the law a serious interference in the internal affairs of China.
Earlier, US President Donald Trump signed into law on democracy and human rights in Hong Kong.
On November 20, the Chinese authorities strongly condemned the adoption by the US Senate of the bill on the protection of human rights and democracy in Hong Kong, which provides for the imposition of sanctions against those who violate human rights.