Prime Minister Boris Johnson will discuss with US National Security Adviser John Bolton a number of security issues, including the crisis with Iran, a spokesman said.
The British spokesman added that Iran must stop its destabilizing activities in the region, but stressed that the British government will continue its commitment to the nuclear agreement signed with Tehran in 2015.
Bolton's talks with British officials focus on three main topics: Iran, China Telecom, Huawei and British-US economic cooperation after the Brexit.
Bolton is the highest-ranking administration official to visit the United Kingdom since Johnson took over as prime minister on July 24.
"I will discuss a series of national security and economic issues with officials in London," Bolton wrote on Saturday before heading to the British capital.
According to US and British media, Bolton is also scheduled to meet Monday and Tuesday with other British government officials, particularly Finance Minister Sajid Javed and Brexit Minister Stephen Barclay.
The British government announced this month that it would take part in a "maritime security mission" alongside the United States to protect merchant ships in the Strait of Hormuz in the Gulf.
On the other hand, the United Kingdom hopes to sign a trade agreement with Washington after leaving the European Union, and US President Donald Trump expressed support for Johnson, and stressed that the two countries have already begun trade talks.