An over 2,000-year-old castle in Gaziantep, Turkey, is said to have been badly damaged in the earthquake.
Several parts of the castle have collapsed, writes the European heritage tribune, EHT.
A mosque in the same area has also been partially destroyed and on the coast a cathedral has collapsed.
In Syria, among other things, the medieval citadel in Aleppo has been damaged.
It is already on the UNESCO World Heritage List.
See some of the damaged cultural heritage in the clip above.