The rapper, who has released several albums and also collaborated with artists such as Kanye West and Ariel Pink, was last seen in Los Angeles in mid-October.
Theophilus London was nominated for a Grammy in 2016 for best performance with the song "All day" together with Paul McCartney.
He was also nominated for this year's bubbler in Sweden's Radio Kulturnytt's best music of the year 2020. The rapper is said to have previously been active on Instagram, but since July he has not posted any posts at all.
“Theo, Daddy loves you.
We miss you.
All your friends and relatives are looking for you.
Wherever you are, send us a signal,” pleads his father, Lary Moses London in a statement.