A scientific scandal hits the wall what science knows about Alzheimer's
Researchers used fake x-rays in research into Alzheimer's disease.
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If you are following what is happening in the scientific arena, finally, with regard to Alzheimer's disease, you are probably wondering about the nature of this mistake that occurred and sparked controversy in the scientific community, regarding ways to treat this disease that affects the mental functions of patients.
The beginning was when a new drug for the treatment of Alzheimer’s was announced in the name of “Adohelm”, and it obtained the approval of the US Food and Drug Administration, and then it turned out that the benefits that accrue from this drug to Alzheimer’s patients are limited, to the extent that insurance companies refused to cover the cost of this drug for most patients. According to the website "Scitech Daily", which specializes in scientific research.
After that, drug companies announced stopping plans to develop a number of Alzheimer's drugs, which they described as promising, after these drugs failed to achieve positive results in clinical trials.
Finally, a major scientific scandal erupted when evidence emerged that some researchers had used fake x-rays in research on Alzheimer's disease, which was published 16 years ago.
This research was so important and reliable that many scholars and researchers later relied on it as the basis for their research work.
The question comes to mind about the connection of all these developments with each other and the extent to which they relate to the development process of drugs for the treatment of Alzheimer's.
And it's all about a protein substance in the human body called amyloid progenitor protein, which is the substance that is deposited on the outer cortex of brain cells and causes the mental functions of patients to deteriorate. for a way to restore patients' mental functions again.
Researchers from the Alzheimer's Treatment Center in the US state of Michigan and other research institutes have spent many years studying this amyloid protein, in order to find answers to know the roots of Alzheimer's and ways to prevent and treat it.
"It's true that amyloid plays a role in brain disease and dementia, but Alzheimer's is complex and involves more than just a single molecule," says researcher Henry Paulson, director of the Alzheimer's Center, who has dedicated the private lab at Michigan Medical School to treating dementia and other dementias for years. ».
The scientific scandal relates to a type of amyloid protein called AB56, which has been described as a toxic protein that encourages plaque formation on brain cells.
Paulson explains that "he did not pay attention to this substance for many years, and he attributed the reason for this to the fact that scientists did not achieve great success in reaching the same results that previous researchers claimed to have reached."
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