China News Service, Guangzhou, August 15 (Reporter Cai Minjie) The combination of HPV vaccination and cervical cancer screening is the best strategy for cervical cancer prevention and control. Increasing the HPV vaccination rate plays an important role in the cervical cancer prevention and control system.

Professor Li Xiaomao, head of the Department of Gynecology at the Third Affiliated Hospital of Sun Yat-sen University, recently gave an interview after giving a lecture at the gynecological oncology academic conference held by the Guangdong Medical Association. He said that China's vaccine technology continues to innovate, and two companies have produced bivalent HPV vaccines. The HPV nine-valent vaccine developed by a number of domestic companies has entered Phase III clinical trials and will be available in the market in about two to three years, which will further ease the shortage of vaccine supply and help accelerate the elimination of cervical cancer globally.

  Human papillomavirus, referred to as HPV, is the main cause of cervical cancer.

Cervical cancer is recognized worldwide as the main "killer" that threatens women's health, ranking fourth in the global female cancer incidence and female cancer mortality rate, and is the only cancer with a clear etiology, preventable and controllable.

HPV is mainly transmitted through sexual contact, and the most common high-risk types that cause cervical cancer are HPV 16 and 18.

  The World Health Organization position paper states: From a public health perspective, bivalent, quadrivalent and ninevalent vaccines are comparable in immunogenicity and efficacy in preventing cervical cancer mainly caused by HPV types 16 and 18.

  In response to the World Health Organization's "Global Strategy to Accelerate Cervical Cancer Elimination" plan to "complete 90% of girls under the age of 15 to complete the HPV preventive vaccine full-course immunization" plan to reduce the incidence of cervical cancer in Guangdong women, Guangdong took the lead in launching HPV for school-age girls Free vaccination work. The project implementation targets are girls under the age of 14 who have a student status in Guangdong Province and who have entered the first grade of junior high school from September 2022 and have not been vaccinated against HPV vaccine. According to the principles of informed, voluntary and free vaccination, HPV vaccine is free of charge. .

  Li Xiaomao said that the prevention and control of cervical cancer in China has a long way to go. The combination of HPV vaccination and cervical cancer screening is the best strategy for cervical cancer prevention and control. The effect is even better. The government has launched free vaccinations for pre-adolescent girls aged 9 to 14. Let’s work together to make good deeds a reality.

  Advances in HPV vaccination and screening technology have made it possible to eliminate cervical cancer.

"But over the years, the incidence of cervical cancer in my country has gradually increased, and the mortality rate has not declined, which shows that cervical cancer screening is insufficient, because most of the cervical cancer detected by screening is in the early stage, and the treatment effect is relatively good." Li Xiaomao said, "One of the problems with cervical cancer screening is that the screening coverage is low. Most of the advanced cervical cancer patients we have received have not been screened. The treatment effect of advanced cervical cancer is naturally not good, and the prognosis is relatively It's bad."

  "Some postmenopausal women think they are too old and feel that there is no need for screening. Women's awareness of self-screening is obviously insufficient, and it is necessary to strengthen popular science education." Li Xiaomao said that if HPV vaccination + cervical cancer screening is implemented well prevention and control strategies, then the goal of eliminating cervical cancer can be accelerated in the near future.

  New methods such as cervical cancer immunotherapy and targeted therapy continue to develop, but the current treatment methods for cervical cancer are mainly surgery, radiotherapy and chemotherapy. It is also very crucial. In addition, in order to improve the level of homogeneous diagnosis and treatment of cervical cancer and strengthen the training of gynecological oncologists, it is also possible to centrally treat cervical cancer patients through the establishment of a medical alliance model of specialist alliances, which is expected to solve the problem. The Lingnan Cervical Cancer Prevention and Control Specialist Alliance established by the Third Hospital is an attempt.

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