• Health A Spanish study points to the new dermatological characteristics of monkeypox: fewer skin lesions, but in areas of sexual contact

  • Interview "Control measures present difficulties: it is impossible to completely trace each chain of transmission"

  • Smallpox The latest news from the infectious outbreak

As new cases of monkeypox are added, more details are coming to light of the new outbreak outside Africa that three weeks ago became a global public health emergency, as decreed by the WHO.

Now,

a new Spanish study points out that four out of ten patients suffer from the complications

of the infection.

In other words,

almost half of the patients suffer from the most severe and disabling forms

of what was previously thought.

Global

cases of monkeypox amount to 26,017,

with nine deaths (two of them in our country), according to statistics updated daily by the World Health Organization (WHO).

These data will have increased since last August 5.

Spain reported a total of 4,942 people last Friday

, of which 139 have been hospitalized and two have died.

Three centers have participated in the study that includes the details of more than 180 patients, Hospital 12 de Octubre in Madrid, the Germans Trias University Hospital-Foundation for the Fight against Infections and the Vall d'Hebron University Hospital, both in Barcelona.

The data has been published today in

The Lancet

.

The most important conclusions highlighted by the authors of the research is that the disease resulting from the virus

frequently manifests itself with atypical forms and complications different from those previously described

, which in 40% of cases require medical treatment.

Eloy Tarín Vicente, assistant doctor of the Dermatology and Venereology service at the 12 de Octubre Hospital, points out to EL MUNDO, that "

one of the most frequent and painful complications, and even a reason for admission, is proctitis

[inflammation of the internal lining of the wall of the rectum], in 25% of cases. This

is followed by tonsillitis, penile edema, and abscesses.

40% of patients required medical treatment, mostly to reduce the pain caused by these manifestations."

In Spain, according to the Health registry, of the 4,436 patients with available information,

139 cases were hospitalized (2.8%)

.

In addition, a total of 237 patients of the 3,546 (6.9%) presented complications throughout their clinical process.

The most frequent were

mouth ulcers and secondary bacterial infections

.

Processes that have also been the object of analysis in this study.

To know more

Health.

Monkeypox: symptoms, how it is spread and keys to differentiate it from another disease

  • Writing: CRISTINA G. LUCIO |

    PILAR PEREZMadrid

Monkeypox: symptoms, how it is spread and keys to differentiate it from another disease

Here, another of the authors, Oriol Mitjà, explains how are the complications that "

produce high intensity pain

, on the one hand, the

inflammation of the anal mucosa

and, on the other, the

ulceration of the palatine tonsils

. The first one produces pain when defecation and the second makes it difficult to swallow food.

They are treated with analgesics and anti-inflammatories of different intensity

and by rectal or oral administration depending on the affectation".

But "in many cases,

we find patients who require admission because they cannot swallow and their pain thresholds are so, so high that they are admitted to be able to prescribe powerful analgesics

", Tarín emphasizes.

Tonsillitis assume that it is due to close contact with infected areas.

The lesions included in the article are also observed in the weekly 'report' of the infection provided by Health: of the cases in which there is clinical information,

six out of ten had anogenital rash (59.4%).

All this draws

an infection far removed from the initial concepts

: mild symptoms that allowed a return to normal life after quarantine.

"We must take into account the new forms of presentation to decide if the current isolations are sufficient or not," says the dermatologist about one of the critical points when it comes to cutting infections.

Again, another work emphasizes the transmission of the virus: "The work we have done

emphasizes the evidence of skin-to-skin contact during sexual intercourse

as the dominant factor in the transmission of monkeypox", Tarin points out.

Last week it was the Spanish Association of Dermatology who, through a study in the

British Journal of Dermatology

, highlighted this fact: fewer skin lesions, but in areas of sexual contact.

Despite the fact that both works bring together small groups of patients, no more than 200, they do suggest that the transmission of the virus maintains a specific pattern far from what was considered until now: an animal-to-human contagion.

Now, it occurs between humans during sexual intercourse mostly.

"

We do not believe that airborne transmission plays a fundamental role, and close contact does.

This influences the measures that must be taken," clarifies the Madrid dermatologist.

One of the points in which Mitjà considers that it is necessary to improve, as they also conclude in the analysis, is in detection.

"In units specializing in sexual health or sexually transmitted infections, good clinical management is done, but it varies from one clinic to another.

There is a lack of clinical guidelines to standardize diagnostic and therapeutic management everywhere

."

This is because monkeypox appears in atypical forms and this requires physicians to have a high index of suspicion for the disease, which can be achieved not only with current protocols but also with epidemiological interviews.

This is so because the work

describes a clinical syndrome related to proctitis, with different clinical characteristics, including systemic manifestations

before the onset of the lesions, in individuals who report anal-receptive sex, which differs from other presentations.

"And this is important, because

this injury is very disabling and painful.

And we need it to be known beyond the weight of the stigma. In this time, we have seen many patients and the emotional issue means that many patients do not consult, do not go to the centres... This is an error that we must correct", emphasizes Turin.

Prophylactic use of virus vaccines

They were not the object of study of his analysis, as Mitjà recalls, but

the vaccines can be a turning point in the course of the infection,

Turín comments.

"We have seen that its use can be more useful in pre-exposure."

The dermatologist explains that through a case in his hospital they have confirmed that "

we still do not know the post-exposure impact

".

The partner of an infected patient was given the vaccine "as a result of close contact in the first few days, but we do not know if he later developed a mild infection due to the vaccine or because it was going to happen that way for other reasons."

In our country there are

currently 5,200 doses that the communities already have

.

Madrid and Catalonia have already put more than a thousand each, and little by little the rest are added.

Most administer it prophylactically in populations at high risk of contagion.

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