According to the World Health Organization (WHO), the health authorities in Ghana have detected two cases of Marburg virus in a laboratory in the capital Accra.
If the infections of two patients from the interior of the country are confirmed, it would be the first outbreak of the particularly deadly Marburg fever in the West African country.
The Marburg virus, which causes hemorrhagic fever, is closely related to the Ebola pathogen and is very dangerous.
At least every fourth infected person dies.
According to the WHO, it is preparing for a potentially larger outbreak.
In addition, the samples are currently being examined by the WHO at the Pasteur Institute in Dakar, Senegal.
Both patients, who were from the Ashanti region but were not related, have died.
Only a year ago, a Marburg virus outbreak occurred for the first time in West Africa, in Guinea.
At that time, only one person fell ill, the man came to a small clinic in the Nzérékoré region in the south-west of the country on August 1 with symptoms and died the next day.
In mid-September, the WHO declared the outbreak over.
An outbreak in Congo between 1998 and 2000 had killed 149 people and killed 123, while in Angola there were 388 people infected and 324 dead in 2004 and 2005.
The virus is transmitted from flying foxes to humans and then through the exchange of bodily fluids and through smear infection.