Health The danger of sharing a mattress with a baby
A team of
Australian researchers has
identified a biochemical marker in the blood that could help detect newborns at risk of
Sudden
Infant Death Syndrome (SIDS), a breakthrough they say creates a pathway for future interventions. prevention of tragedies.
In their study, babies who died of SIDS had lower levels of an
enzyme
called butyrylcholinesterase (BChE) shortly after birth, the researchers said.
BChE plays an important role in the
brain's activation
pathway , and low levels would reduce a sleeping baby's ability to wake up or respond to her environment.
The findings are a
game
changer, offering not only hope for the future, but also answers for the past,
study
leader Dr. Carmel Harrington, of Westmead Children's Hospital in Australia, said in a statement.
"A seemingly healthy baby who
falls asleep and doesn't wake up
is every parent's nightmare and until now there was no way of knowing which baby would succumb," Harrington said.
"But that is no longer the case. We have found the first marker that indicates
vulnerability
before death."
Using dried blood spots taken at birth as part of a
newborn screening
program , Harrington's team compared BChE levels in 26 babies who later died of SIDS, 41 who died of other causes, and
655 survivors.
Research
The fact that levels of the
enzyme
were much lower in infants who died of SIDS suggests that they were inherently vulnerable to dysfunction of
the autonomic nervous system
, which controls the body's unconscious and involuntary functions, the researchers said.
The Network of Children's Hospitals in Sydney, Australia, has described the discovery as "a
pioneering advance
in the world".
Failure to
wake
when appropriate "has long been considered a key component of a baby's vulnerability" to SIDS, the research team in The Lancet's eBio Medicine said.
SIDS is the unexplained death of an apparently healthy baby
while sleeping.
Harrington lost her own son to SIDS 29 years ago and has dedicated her career to researching the condition, according to the statement.
"Further
research
is urgently needed" to determine whether routine BChE measurement could potentially help prevent future SIDS deaths, the researchers said.
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