The Portuguese public prosecutor's office is focussing on its investigation into "Maddie".
A German suspects had been formally accused, the prosecution in Portimão said Thursday.
They did not specify the identity of the accused.
Maddie McCann disappeared on 3 May 2007 shortly before her fourth birthday from the home of her family in a resort on the southern Portuguese Algarve coast while her parents ate at a restaurant in the evening.
Despite large-scale international manhunts the case was never solved, missing from the girl to date each track.
In June 2020, there was a surprising turn of events: the public prosecutor's office in Braunschweig announced that they were investigating the murder of the German Christian B.
He has a criminal record for sex offenses and lived regularly in the Algarve from 1995 to 2007.
Suspect already in custody several times
The suspect's lawyer, Friedrich Fülscher, told the Bild newspaper on Thursday: "The step taken by the Portuguese authorities should not be overestimated." to stop in Portugal.
A spokesman for the prosecutor's office Oldenburg confirmed the Bild newspaper the input of a request for judicial assistance from Portugal.
As is currently serving a seven year sentence for the rape from a 72-year-old woman.
He had been delivered in 2017 child sexual abuse on the basis of a European arrest warrant from Portugal to Germany.
After a were serving prison sentence, he left Germany in 2018, but a year later was delivered again from Italy.
This was based on a second European arrest warrant had been issued for a drug offense.