“Rejuvenate, masculinize and diversify” bone marrow donations.
This objective would increase the chances of success of the transplants, explained Friday the Agency of biomedicine which manages the register.
In 2021, the number of registrations rose again with 23,769 new registrants, compared to 16,331 donors in 2020, bringing the register to 338,000 registrants.
In early 2022, the agency also noted an “unprecedented” increase in registration requests following the call, widely relayed on social networks, from a mother to save her three-and-a-half-year-old child, Joseph , suffering from acute lymphoblastic leukemia.
An “exceptional” momentum
In a few weeks, 91,000 pre-registration requests were recorded.
Welcoming this “exceptional” momentum, the Biomedicine Agency now wants to ensure that donors are well informed about donation and that their commitment continues over time.
“There are still misunderstandings: we may never be called and, if we are, it will be for a patient we will never know,” recalled Evelyne Marry, director of sampling at the agency, during a press briefing.
64% of registrants are women
Another objective of the agency: to mobilize donors who offer the best chances of recovery.
She thus wishes to “rejuvenate, masculinize, diversify” the profiles.
"The younger you are, the more the transplant has a chance of taking", explained the director of the agency Emmanuelle Cortot-Boucher.
A donor is usually contacted eight years after registration, hence the interest in registering as soon as possible, she said.
In 2021, the agency lowered the age limit for registration to 35, from 50 previously.
Another imperative: to masculinize the profiles.
Today, 64% of registrants are women, yet in 70% of cases, grafters choose men.
Donors “from diversity”
Indeed, grafts work better with men because they do not have the antibodies developed by women during pregnancy which complicate the good tolerance of the graft.
Finally, the agency absolutely wants to diversify donor profiles.
“Each patient has their own genetic profile, determined by their origins and family genetic history,” explained Emmanuelle Cortot-Boucher.
Reaching donors "from diversity" would make it possible to "meet the needs of all patients": "the register must reflect the diversity of French society", she insisted.
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The survival of Joseph, leukemia at 3 years, depends on a bone marrow donation
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