France would have nearly 700,000 people with epilepsy, of which around 30% would present resistance to existing treatments.

However, according to a recent study CBD seems to have very positive effects on children with refractory epilepsy.

The deadline for the experiment in 2023 poses the challenge of the generalization of antiepileptic treatments based on CBD.

A two-year study

Under the control of the National Medicines Safety Agency (ANSM), experimentation with cannabis for medical use was launched for two years in March 2021 in France.

In total, it must include up to 3,000 patients.

Regarding refractory epilepsy, “we have positive feedback on the effectiveness of treatments (…) but there are always undesirable effects, it is relative to any drug”, recognizes Nathalie Richard, who directs the work of the ANSM, following a meeting of the Temporary Scientific Committee (CST), responsible for monitoring the experiment.

No quick fix

"CBD should not be seen as a magic drug", however warns Stéphane Auvin, neuropediatrician at Robert Debré Hospital.

The latter doubts that the treatment can relieve all forms of epilepsy.

“CBD as a molecule in the treatment of epilepsy clearly has its place” but “does an experiment conducted by the ANSM give the same legitimacy as a clinical trial to measure side effects and efficacy?

asks the neuropediatrician.

The device must be the subject of a precise evaluation, underlines the ANSM, in particular on the repercussions of medical cannabis on other treatments.

One certainty, the patients treated as part of the experiment will continue to be treated "with medical cannabis" once it has ended.

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  • Therapeutic trial

  • epilepsy

  • Cannabis

  • Health

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