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After two years of pandemic, the coronavirus has evolved to overcome its main threats: vaccines and herd immunity. The virus mutates and transforms into new variants, with new, increasingly rapid incubation times and new symptoms, in some cases milder but with greater contagion capacity. After the wave of

omicron

, which has already spread widely throughout Europe, new names such as

deltacron appear

. This is the last hour of the new variants of the

Covid

.

The

Cyprus

authorities have reported 25 cases of Covid associated with a new variant, which they have called deltacron, and which would be a kind of mix between some omicron and other

delta

mutations , but some question this classification.

Professor

Leondios Kostrikis

, professor of biology at the

University of Cyprus

and director of the

Laboratory of Biotechnology and Molecular Virology

, argues that cases of

deltacron

are more frequent among patients hospitalized for

Covid

.

Last Friday, the genomic sequences of the

coronavirus

obtained in Cyprus were sent to the international

Gisaid

database of

the Pasteur Institute

in Paris.

Nothing is known yet about the characteristics that this composite variant could have: if it will be more contagious, more lethal or, simply, if it will manage to undermine

omicron

, which seems quite unlikely given the rapid infection capacity of this variant, which has allowed to prevail over all others.

A laboratory error?

However, other scientists have later suggested that Leonidos Kostrikis' findings are the result of cross-contamination in the laboratory. The professor has refuted the criticism, also recalling that "at least one sequence from

Israel

deposited in a global database shows the genetic characteristics of

deltacron

."

Beyond the discrepancies, it is normal for the virus to change continuously and many mutant sequences are sent to the databases that collect genomes: however, in almost three years of the pandemic there are only five variants reported as "worrying" by the

World Health Organization

(WHO) and some of them have disappeared, supplanted mainly by

delta

and

omicron

.

The "twin" of omicron

Of great interest is a sister variant of

omicron

that may have developed autonomously around the same time and that researchers are monitoring.

To define it, the researchers have created two sublineages of

B.1.1.529

: BA.1, that is,

omicron

, and the new "anomalous" lineage called BA.2.

The alarm has come from

Denmark

: BA.2 may have become dominant over BA.1.

The country is one of the best in the world in terms of number of sequences and local data reported on the international sequencing portal Gisaid shows a massive growth of the "new" lineage.

In recent days, numerous BA.2 genomes have also been reported from

South Africa

,

Australia

, and

Canada

. Currently, the largest number of sequences related to the variant in question come from 82% from Denmark, 7% from Sweden, 3% from India. Both sublineages have almost all the

spike protein

mutations initially detected for

omicron

, but the BA.2 lineage maintains some

delta

.

It is difficult to differentiate from

omicron because it does not have the

S gene

deletion

that allows us to suspect that it belongs to the

omicron

variant directly from the test.

In order to identify the BA.2 variant, it is necessary to sequence all the samples, and this implies a laboratory capacity that not all countries have.

That is why the Danish data is important.

Also in this case it is necessary to wait and continue monitoring: many variants have been born and have been confined in some areas without spreading or generating concern.

The Ihu variant

Recently, another variant called

B.1.640.2

has been identified in the

Ihu Méditerranée Infection

in

Marseille

and renamed precisely as IHU.

The mutations it presents would have 46, 37 deletions, therefore more than

omicron

.

In any case, it seems a variant limited to the 12 patients under surveillance: the WHO expert

Maria Van Kerkhove

recalled that the "mother" of this subvariant, B.1.640, was already classified in her day as a

"variant in follow-up"

(VUM) in November, which would suggest that it does not have the ability to supplant the predominant variants.

According to the criteria of The Trust Project

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