China News Finance, January 8th (Reporter Zhang Ni) Recently, the U.S. Department of Health and Human Services released the 15th edition of the carcinogen report, which added 8 new carcinogens. Chronic Helicobacter pylori infection was listed as a clear carcinogen .
The news drove the A-share "anti-Helicobacter pylori concept stock" to set off a daily limit wave. At the same time, the approval of the "consumer self-test" product also attracted attention from the outside world.
Data map: A staff member of a hotel puts chopsticks on the table.
Photo by Liu Wenhua
Helicobacter pylori is listed as a "clear carcinogen", the infection rate of Chinese people is more than half
Helicobacter pylori is a microaerobic gram-negative bacillus that can be spread through sharing dishes, toothbrushes, and even kissing. It is a bacterium that can colonize the human stomach for a long time and cause chronic inflammation.
According to conservative estimates from the World Gastroenterology Organization (WGO), at least half of the world’s population is infected with Helicobacter pylori.
China is the country with the largest number of Helicobacter pylori infections, with an infection rate of 59%.
"Helicobacter pylori is a major risk factor for gastritis, peptic ulcer, and gastric malignant tumors. It may also be related to anemia, thrombocytopenia, diabetes and other diseases." Chen Ning, deputy director of the Department of Gastroenterology, Peking University People's Hospital, told a reporter from China New Finance.
Judging from the incidence of gastric cancer in my country in recent years, this can also be confirmed.
According to the "Report on Nutrition and Chronic Disease Status of Chinese Residents (2020)" released in December 2020, the top five cancer deaths are lung cancer, liver cancer, gastric cancer, esophageal cancer, and colorectal cancer.
According to the fifth national consensus report on the treatment of Helicobacter pylori infection, about 15%-20% of patients with Helicobacter pylori positive in the country will develop peptic ulcers, 5%-10% will develop dyspepsia, and about 1% will develop gastric malignancies. .
Almost all patients with Helicobacter pylori positive have chronic active gastritis.
"Helicobacter pylori is very stubborn. Once infected, the self-healing rate is close to zero unless a formal treatment is used. There are problems with gastroscopy, a family history of gastric cancer, and peptic ulcers. Helicobacter pylori must be eradicated."
Chen Ning said that for patients who have undergone gastric surgery, have gastric discomfort, or have gastric cancer in their first-degree relatives, it is recommended that they be tested for Helicobacter pylori.
The diagnosis methods include traumatic and non-traumatic.
The former relies on gastroscopic biopsy, including rapid urease test, gastric mucosal tissue section staining microscopy, bacterial culture, etc.; non-invasive detection methods include 13C or 14C breath test and serum antibody detection.
Helicobacter pylori treatment drug sold on an e-commerce platform.
Listed companies are "rubbing" hot spots, and some toothpastes claiming that "anti-you" has been cracked down by the Drug Administration
"Helicobacter pylori is listed as a clear carcinogen by the United States" also drove the A-share "anti-Helicobacter pylori concept stocks" to set off a daily limit wave. Many listed companies began to "crush" Helicobacter pylori hot spots, and businesses hyped "anti-helicobacter toothpaste." .
On the 5th, SDIC Zhonglu said on the investor interactive platform that the anti-H. pylori-related products are still in the research and development stage, and there are certain uncertainties in the commercial prospects, reminding investors to pay attention to investment risks.
On the 6th, Ruizhi Pharmaceutical introduced on the investor interactive platform Interactive Yi. The company’s fructooligosaccharides and galactooligosaccharides are typical high-quality prebiotics. At present, foreign studies have shown that prebiotics can assist in the elimination of Helicobacter pylori drugs to improve the elimination rate , But the company has not conducted relevant research, and it is currently unable to confirm whether it can cooperate with drugs to treat Helicobacter pylori.
Juneyao Health issued an announcement a few days ago that the company’s main business is still lactic acid bacteria drinks, and the company’s products such as chewable tablets and drinks in the Helicobacter pylori field are still in the product launch stage.
In addition, the reporter noticed that some businesses have recently hyped that "anti-you toothpaste" can kill Helicobacter pylori and prevent gastric cancer and other gimmicks, selling the so-called "anti-you toothpaste" on e-commerce platforms.
However, on the 7th, the State Food and Drug Administration issued a response stating that the toothpaste claim to be "anti-H. pylori" lacked scientific basis.
Products such as toothpastes that claim to be "anti-H. pylori" may contain broad-spectrum antibacterial agents.
If the broad-spectrum bacteriostatic agent is used in large quantities for a long time, it may cause the disorder of the oral flora, which is not conducive to oral health.
Screenshot of the official website of the State Food and Drug Administration
Enterprises push testing products, can Helicobacter pylori be self-tested at home in the future?
Just recently, the approval of a Helicobacter pylori detection product has also attracted great attention from the outside world.
A few days ago, Nuohui Health announced that its Helicobacter pylori detection product, Helicobacter pylori, became China’s first Helicobacter pylori detection product approved by the National Medical Products Administration for "consumer self-testing".
Prior to this, all approved products for Helicobacter pylori testing were limited to testing by professional medical personnel in medical units.
According to the company, this product uses a double antibody sandwich method to detect the presence of Helicobacter pylori antigen in stool samples.
The product realizes the integrated design of “pregnancy test stick” for sampling and testing. It is easy for users to operate, painless and noninvasive. There is no need to take medicine before testing, and no need to fasting during testing. There are no special requirements for sample collection. After sampling, the sample stick is inserted into the reagent tube. , Shake well for 10 seconds, and the result can be read 10 minutes after pressing the cap of the tube.
In terms of detection accuracy, the company revealed that the registered clinical trials conducted in three tertiary clinical hospitals of Zhejiang University School of Medicine Affiliated Run Run Hospital, Zhejiang Provincial People's Hospital and Peking University Shougang Hospital included a total of effective subjects suspected of Helicobacter pylori infection. There were 1644 cases with a sensitivity of 96.5% and a specificity of 99.1%. The self-test results of the subjects were compared with those of professionals, and the coincidence rate reached 100%.
Affected by this news, on January 7, Nuohui Health's share price rose more than 40%.
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