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When the famous 007 secret agent asks for his cocktail, he always says
"mixed, not shaken"
.
And when you go to a vaccination point against
Covid19
it is easy that, like James Bond himself,
that third booster dose is also of a mixture without shaking
.
There are many people who these weeks are surprised to see that the mark of that third dose does not coincide with the two that they have previously received, something that even causes some people to leave the vaccination center without their dose for fear of the mixture .
If you want to know everything about the third dose 'mixed, not shaken', I invite you to continue reading.
What brand is the third dose?
Currently,
the booster vaccines that are being administered in our country are messenger RNA vaccines, that is
, those from the
Pfizer and Moderna
laboratories
.
If you have the same brand, your vaccination is known in health slang as homologous.
If they have given it a different brand, it is a heterologous vaccination.
Why can vaccines now be mixed?
When the mass vaccination was carried out to obtain the complete schedule,
if the first dose had been from Pfizer or Moderna, the mark for the second was respected
.
But with AstraZeneca this was no longer the case, and for the second dose there was the option for some population groups to switch to Pfizer.
This
was done after several studies worldwide in people who had not had Covid
, and it was shown that not only was it a safe practice but it even seemed to increase the effectiveness of vaccines.
The passage of time and studies have shown that heterologous vaccination produces enhanced immunity.
What does the European Medicines Agency say?
Both this Agency and the European Center for Disease Prevention and Control, as well as the World Health Organization,
endorse the mix and match of different brands of vaccines against Covid.
But
not only in the booster dose, in the third, but also in the initial vaccination.
If you were vaccinated for the first time now, it would not be strange that those two doses were from different laboratories.
Is this the first time vaccines have been mixed?
Not at all.
Mixing vaccines against the same disease, or heterologous vaccination, is something that began to be done several decades ago.
It
is
generally
done with the aim that people develop higher levels of immunity,
compared to what they would obtain if they received vaccines with the same formula.
Can Pfizer be mixed with Moderna?
Yes. And according to the latest scientific evidence we have, it
is even positive;
since it would increase a little more the level of neutralizing antibodies
obtained if we compare it with those that we would develop if in the third dose we were administered that of Pfizer.
And Modern with Pfizer?
Yes. If the first two doses we received were from Moderna and now they give us the booster with Pfizer, no problem.
According to the latest studies, it
seems that it would even be preferable to receive the one from Pfizer
because the protective response that we will develop is a little better than if it had been with Moderna.
And with AstraZeneca?
Science tells us that it
is completely safe to mix AstraZeneca vaccine with Pfizer or Moderna
.
Furthermore, it seems that even this mixture is recommended to obtain a robust response in terms of the level of neutralizing antibodies.
And with Janssen?
Exactly the same as in the case of AstraZeneca:
safe, effective and even it seems that recommended
.
Is it better to mix or not to mix?
My recommendation is that this
should not be something that you are not overly concerned about.
If your first vaccination was with Pfizer and now they have named it Modern, great.
If it was with Pfizer and now they have managed the same brand, great too.
The important thing is to get vaccinated
, and the concern about the name of the laboratory should be in the background.
According to the criteria of The Trust Project
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