According to a study by the Mainz University Medical Center, 40 percent of people who have become infected with the coronavirus have long-covid-like symptoms six months after the infection.

This affects both people who are knowingly infected and people who are unknowingly infected, said study director Philipp Wild on Monday in Mainz.

He presented the first results on the long-term effects of the Sars-Cov-2 infection. 

10,250 people between the ages of 25 and 88 were examined for the study. To a large extent, the researchers were able to fall back on data that had already been collected in advance. Participants included knowingly and unknowingly infected people as well as people without an infection. 

A key finding: around one in three infected people stated that they had not yet returned to their original level of performance before the pandemic.

29.8 percent of those knowingly infected and 22.4 percent of those unknowingly infected reported it.

At the same time, however, 22 percent of people who had not gone through an infection also said they felt less healthy than before the pandemic and experienced symptoms.

The reason for this is that the most common long-covid symptoms such as fatigue, shortness of breath or fatigue are so unspecific, said Wild.

There is still no uniform clinical pattern.

Women more often affected

According to the study, there is a connection between Long Covid and acute infection: the more symptoms occur during the acute illness, the higher the likelihood that Long Covid symptoms will follow.

Most complaints decrease over time.

"Many of the complaints will subside, but there remains a group that has persistent complaints," said Wild.

According to the information, women are more often affected by Long Covid than men.

But there is no age relationship.

Older people are not affected significantly more often than younger people. 

Moderate or severe impairments

According to the information, 61.9 percent of the study participants knew about their infection at the beginning of the examinations, 35.1 percent did not.

More than 90 percent of all infected people had not required medical treatment, 3.5 percent were treated on an outpatient basis, and a further 5.8 percent were inpatient.

In the knowingly infected, the disease progression remained mild at 51.9 percent;

6.9 percent had no symptoms.

In the unknowingly infected, 48.2 percent of the cases were mild.

However, every fourth person knowingly infected and every fifth person unknowingly infected suffered moderate or severe impairments.

The researchers want to investigate the effects of Long Covid in another study.

Among other things, they want to clarify whether corona vaccinations can protect against the long-term consequences.

The first results can be expected in the second quarter of 2022.