• Direct.

    Coronavirus today

  • Immunization.

    The effectiveness of Pfizer vaccines decreases after 90 days: the risk of infection is almost 3 times higher at 5 months

  • Pandemic.

    Questions and answers about pediatric vaccination against Covid-19

The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has given the

green light to vaccinate children aged 5 to 11 years

with the Pfizer and BioNTech vaccine for Covid-19.

The indicated dose will be one third of that approved in people 12 years of age or older (10 µg versus 30 µg).

As in the other age groups, it is given as two intramuscular injections in the upper arm.

The EMA bases its position on the basis of a

phase III clinical trial

in children aged 5 to 11 years that showed that the immune response (according to antibody levels) to the 10 µg dose was comparable to that of the 30 µg in population 16 to 25.

In total, almost 2,000 children between the ages of 5 and 11 who had no signs of previous infection participated.

Of the 1,305 children who received the vaccine, three developed Covid-19 compared to 16 in the placebo group, which shows an

effectiveness of 90.7%

.

The most common side effects were pain, redness, and

swelling at the injection site

, tiredness, headache, muscle pain, and chills.

These effects are usually mild or moderate and improve within a few days of vaccination.

According to the criteria of The Trust Project

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