If I got the same vaccine, but someone got really sick, and I didn't get sick at all, would it have been the water vaccine for me?



Before giving this answer, let me explain why each person gets the same vaccine and gets sick differently.



This is alcohol.



Even after drinking the same drink, some people get red and tired even after drinking just one drink, while others look fine even after drinking several bottles.



The same goes for coffee.



Some people have a good night's sleep with just one drink, and some people get a good night's sleep with just a few drinks.



This is because each person has different genetic characteristics that respond to alcohol and caffeine.



The same goes for vaccines.



Vaccines contain dozens of auxiliary substances in addition to the core substances that build immunity.



When you get vaccinated, these substances first pass through your muscles, then into your bloodstream, spread through your body, and then into your brain.



However, each person reacts differently to different substances, reacts in different stages, and reacts to different degrees.



So each person has different genetic characteristics, so even if you get the same vaccine, some will get sick more and some will get less.



Is this all? no. There is another reason.



Columbia University in the United States gave the same electrical stimulation pain to 11 people, but each person responded differently.



When I took an MRI of the brain, the brain reaction, that is, the emotion itself, was different.



In other words, even with the same pain, depending on the person's psychological state, some feel pain and some feel less pain.



This can be said to the extent that it is possible.



Let me explain with Pfizer and Moderna. Both vaccines are mRNA vaccines.



Moderna has more than three times the amount of mRNA than Pfizer.



From what we've studied so far, Moderna is twice as likely as Pfizer to report headaches or fatigue after being vaccinated.



Instead, Moderna produced more neutralizing antibodies than Pfizer.



The words No pain, No gain are not entirely wrong.



Now, going back to the first question, is it a vaccine that doesn't only hurt me, or a water vaccine for me?



no. Even if it passed without much pain, it is not a water vaccine.



Obviously, there is a difference in pain from person to person, but it is only a difference depending on the psychological state and individual constitution, and it did not lead to a big difference in the formation of neutralizing antibodies.



Recently, there has been a study that neutralizing antibodies, not just large amounts, can at least fight hard.



It's about quality rather than quantity.



If you are a little more sick, there is a possibility that you have more neutralizing antibodies, but that does not mean that you have acquired strong immunity.



If it hurts or not, you don't have to worry too much.



However, there are individual constitutions that must be taken care of.



If you have a constitution with HPF4 antibody, the blood will harden if you administer a drug called heparin, which prevents blood from clotting. In this case, the risk of blood clots is high.



You should make a decision carefully after consulting with your doctor.



(Video coverage: Kim Hyun-sang, Park Hyun-cheol, video editing: Kim Jun-hee, CG: Kang Kyung-rim)