Many Internet users see it as a scientific "bomb", dropped in the middle of summer: the alleged recognition, by the Pasteur Institute, of the effectiveness of Ivermectin in the treatment of Covid-19 in humans .
To believe the defenders of this cheap antiparasitic drug, a study recently published by the French institute would finally prove its usefulness.
However, the research in question simply shows a minimal effect on the symptoms of the disease in an animal model.
For the defenders of Ivermectin, this antiparasitic drug with alleged beneficial effects against Covid-19, the summer of 2021 was marked by a real consecration: the recognition, by the Pasteur Institute, of its effectiveness.
"The Pasteur Institute has just validated Ivermectin to cure Covid ... We have been preventing this inexpensive treatment for months to promote vaccines with side effects and costly ... Wake up the French ...", enthuses as well one Internet user among others, when an e-mail chain states: “Excellent news.
The Institut Pasteur recognizes the efficacy of Ivermectin.
A single intake could in some people eradicate all the genetic material of SARS Covid-19 (sic) ”.
The Pasteur Institute has just validated ivermectin to cure Covid ...
This inexpensive treatment has been prevented for months to promote vaccines with side effects and expensive ...
Wake up the French ... pic .twitter.com / wnGGG8Gmst
- GoldoFrance 🇫🇷 (@ SAMUEL40057369) August 2, 2021
However, if the French institute published, on July 12, an article entitled
Ivermectin alleviates the symptoms [of] Covid-19 in an animal model
, this summary of the study conducted by its researchers only recognizes certain limited virtues of the antiparasitic in ... hamsters.
A simple reading of the article in question shows that the institute has never claimed that Ivermectin would cure Covid-19 in humans.
“Researchers from the Institut Pasteur have studied in the laboratory the impact of a molecule, ivermectin, on the clinical symptoms of Covid-19 in an animal model. […] [They] have shown that taking this drug at standard doses reduces the symptoms and severity of SARS-CoV-2 infection in an animal model ”, explains one of the first paragraphs. .
Just before a major clarification: "The results of the study reveal that ivermectin acts on the modulation of the immune response in animal models infected with SARS-CoV-2 and thus makes it possible to reduce inflammation at the level of respiratory tracts.
This immunomodulatory effect is involved in reducing the appearance of symptoms of the disease.
Researchers have also shown that the molecule reduces the risk of loss of smell.
However, they observed that ivermectin treatment did not act on viral replication of SARS-CoV-2.
No impact on virus replication
And one of the study's authors, Guilherme Dias de Melo, explains: “Surprisingly, we observed that ivermectin treatment did not limit viral replication, both treated and untreated models. had similar amounts of viral load in the nasal cavity and lungs.
Our results reveal that ivermectin has an immunomodulatory and not an antiviral effect.
For the Pasteur Institute, this drug - whose use by the WHO against Covid-19 last March - could therefore potentially, after validation by clinical trials in humans, "[relieve] inflammation and symptoms ”of Covid-19 without having“ impact on the replication of SARS-CoV-2 ”.
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