German researchers have discovered the cause of blood clots for some of those who received the vaccine
German researchers said today that they believe, based on laboratory research, that they have found the cause of rare and dangerous blood clots in some of those who received Covid-19 vaccines produced by AstraZeneca and Johnson & Johnson.
In a study not yet reviewed by experts, the researchers said that Covid-19 vaccines that use adenovirus vectors (cold viruses used to transport vaccine materials) send some of their components to the nucleus of cells, where an error may occur in reading some instructions for making Corona virus proteins. They indicate that the resulting proteins may lead to coagulation disorders in a small number of recipients.
Scientists are working as drug agencies in the United States and Europe are searching for an explanation for what causes rare clots, but they may be fatal and are accompanied by low platelet counts, prompting some countries to stop or limit the use of the AstraZeneca and Johnson & Johnson vaccines.
“We support research and ongoing analysis of this rare case while working with health experts and health authorities around the world,” Johnson & Johnson said in an emailed statement.
We look forward to reviewing and sharing the data as soon as it becomes available. ”
AstraZeneca declined to comment.
The researchers at Goethe University in Frankfurt and other sites explained in their research paper that vaccines use a different technology known as messenger RNA, such as the one developed by Biontech with Pfizer, and which was also developed by Moderna, which transfers the genetic material for the Corona virus protein to the fluids inside cells only. And not to the nucleus of cells.
The paper suggests that vaccine manufacturers who use adenovirus vectors modify the protein sequence "to avoid unintended interactions and to increase safety."
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