According to a study conducted by the Spanish Institute of Health, being vaccinated against Covid-19 with two different vaccines is not dangerous.
On the contrary, the level of antibodies at the end of the study is very important and the effectiveness could even be higher.
An additional study will be carried out in France.
While the vaccine campaign against Covid-19 is accelerating, some are wondering about the relevance of having a second dose of vaccine against Covid-19 different from the first.
Some healthcare workers under the age of 55 have received a dose of messenger RNA vaccine after a first injection of AstraZeneca.
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A study conducted by the Spanish Institute of Health brings rather reassuring results.
440 patients were followed after receiving a Pfizer vaccine, followed by a dose of AstraZeneca.
They had a few side effects, like headaches or chills, but nothing serious.
"We are not playing sorcerer's apprentice"
“A lot of people were worried about this lead and felt like we were doing a little unusual things. We are not playing sorcerer's apprenticeship. It was a strategy with a real scientific rationale. Spanish study confirms that tolerance is good and that efficacy is more interesting since the level of antibodies at the end of the study is very high ", explains Professor Jean-Daniel Lelièvre, head of the immunology department at Henri-Mondor hospital in Créteil, at the microphone of Europe 1.
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By combining different vaccines, the efficacy could even be higher, but it is still too early to conclude. In France, studies will soon provide additional results on this combination, AstraZeneca then Pfizer, but also on the succession of two different messenger RNA vaccines.