A group such as the University of Tokyo succeeded in an experiment using mice to improve the function of the body by killing "senescent cells" which are considered to be one of the causes of aging-related deterioration and illness. Announced.
This research was published in the American scientific journal "Science" by a group of Professor Makoto Nakanishi of the Institute of Medical Science, University of Tokyo.
Cells that have stopped dividing due to aging, etc., do not work normally and are said to cause deterioration of body function and illness, and are also called "senescent cells".
The group found that the "senescent cells" died when the protein "GLS1" stopped working, and gave older mice a drug to stop the protein from working.
As a result, it was confirmed that the "senescent cells" of the mouse actually died and the symptoms such as abnormal blood sugar level and arteriosclerosis improved.
In an experiment to find out how long a mouse could be held by a stick,
it took about 200 seconds for young mice and about
for older mice, but the drug was administered to older mice. Then it extended to about 100 seconds.
Professor Nakanishi said, "There is a possibility that the health problems caused by aging can be eliminated and the healthy period can be extended. Since the mechanism of aging is often unknown, we will continue our research and put it to practical use in humans. I want to aim for aging. "