A new type of coronavirus vaccine that has begun to be inoculated overseas.
What is worrisome is the information that some people have allergic symptoms.
Is it okay to inoculate?
I have summarized what I know now based on reports from specialized agencies in the United States.
(International Department Reporter Genki Kitai, US General Bureau Reporter Tetsutaro Soe)
Q. Should I get the vaccine?
The CDC = Centers for Disease Control and Prevention in the United States recommends vaccination, saying on January 6 that the person in charge said, "The benefits of vaccination outweigh the risk of new coronavirus infection."
Vaccines developed by major pharmaceutical companies such as Pfizer are scheduled to be supplied to Japan, and in the United Kingdom, where vaccination began on December 8, the earliest in the world, 1,296,432 people will be the first to be vaccinated by January 3. Was inoculated.
In the United States, 1,893,360 people received their first vaccination between December 14th and 23rd.
So far, at least two people in the United Kingdom and at least 21 people in the United States have been found to have had a severe allergic reaction called post-vaccination anaphylaxis.
However, the inoculation has been continued with caution since then.
Q. How often do you have severe allergic reactions?
to the report released by the CDC on January 6, 1,893,3.6 million vaccinations resulted in 21 cases, so 1 million vaccinations accounted for 11 cases.
Q. Is it expensive compared to vaccines for other diseases?
According to the information as of January 6th of the CDC, the rate of anaphylaxis symptoms in influenza vaccination is 1.3 per million times.
The rate of this symptom occurring with this new coronavirus vaccine is calculated to be about 10 times higher, but a CDC representative said, "It is still an extremely rare and extremely safe vaccine."
In addition, since vaccination has just begun and data are limited, there is a limit to the risk comparison with other vaccines.
Q. Who showed the symptoms of anaphylaxis?
Of the 21 people who showed symptoms of anaphylaxis, 17 had allergic reactions to drugs or food in the past.
▼ Ages range from 27 to 60, with a median of 40.
▼ 90% are women.
▼ There is no regional bias.
Q. How long does it take for symptoms to appear after vaccination?
The time until symptoms appear is
▼ 71% (15 people) within 15 minutes,
▼ 14% (3 people) 15 to 30 minutes,
▼ 14% (3 people) 30 minutes or more, the most The late one was two and a half hours later.
Q. Did the symptom recover?
According to the report, some of the 21 were hospitalized, but all 20 who could be tracked afterwards had either recovered or were discharged.
So far, no deaths due to anaphylaxis after vaccination have been reported.
Q. What causes allergic reactions?
cause has not yet been identified, but the US FDA (Food and Drug Administration) decided to investigate in December, saying that the substance PEG = polyethylene glycol contained in this vaccine may be involved. Shown.
According to a review published in the world-famous American medical journal "New England Journal of Medicine", polyethylene glycol is a compound used in pharmaceutical products, and its relationship with allergic reactions has been pointed out. That is.
The CDC states that people who are allergic to polyethylene glycol or its closely related substance, polysorbate, should not be vaccinated against mRNA.
Q. What are the reported symptoms other than anaphylaxis?
According to the report, the total number of health reports, including those that are not known to be related to vaccines, was 4393, or 0.2%.
Within one day of vaccination, 83 people had a non-anaphylactic but allergic reaction, of which 72 had relatively mild symptoms.
In addition, 67%, or 56 people, had allergic reactions to drugs or food in the past.
Symptoms were often itching, rash, and mild respiratory symptoms.
The age of those who showed symptoms ranged from 18 to 65 years, with a median of 43 years and 90%, or 75, were women.
It took 85% of the time for 61 people to develop symptoms within 30 minutes after vaccination, and 11 people after 30 minutes or more, and the remaining 11 people were unknown.
Q. Should people with allergies not be vaccinated?
CDC says that even people who have had allergic reactions to food or pets do not need to avoid vaccination.
On the other hand, the following people need to be careful.
▼ If you experience allergic symptoms such as anaphylaxis, hives or respiratory distress within a relatively short period of time due to the ingredients contained in the vaccine, we encourage you not to inoculate.
▼ In addition, if the first inoculation causes symptoms of anaphylaxis, we are calling for avoiding the second inoculation.
CDC provides at least 30 minutes for people who have had anaphylactic symptoms with other vaccines or injections in the past, or who have had allergic symptoms in a relatively short period of time, in case of severe allergic symptoms. It is necessary to observe the health condition on the spot and to see if there is any change in physical condition for 15 minutes after inoculation for other people.
Q. How does the CDC evaluate the results of vaccination so far?
On January 6, the CDC said, "There are no alarming signs so far," and will continue follow-up, including anaphylaxis, and regularly assess the benefits and risks of vaccination. I'm going.
And since the mortality rate of high-risk people such as the elderly from the new coronavirus infection is high and treatment options are limited, it is important to inoculate a wide range of highly effective vaccines in order to suppress the pandemic. It is said that.
And as a preparation for vaccination, it is necessary to secure enough medicines to deal with anaphylaxis and to treat immediately if the onset is suspected.
Q. Are women more likely to have allergic symptoms?
(Reporter) According to the
report, 62% of the inoculated people are female, 34% are male, and the rest are unknown.
90% of the people who showed symptoms of anaphylaxis were women, but the CDC is cautious about the gender difference in symptoms, saying that it may be due to the fact that more women were vaccinated. is showing.
Regarding the report itself, the CDC is a system that medical staff and vaccinated people voluntarily report, that it may be affected by heightened safety concerns, and that the data There is a possibility that the actual situation may not be reflected correctly due to the time difference of the compilation, and there is a certain limit.
Q. How do you know this information?
(Reporter) In the
United States, health problems that occurred after receiving various vaccines including the new coronavirus using the "VAERS = Vaccine Adverse Event Reporting System" operated by the FDA together with the CDC. We are collecting information related to.
This system allows anyone, including healthcare professionals, vaccinated people and parents, to report, including those for which it is unknown whether the vaccine is the cause.
The CDC and others will investigate what is suspected to be related to the vaccine and investigate the cause.
The new coronavirus vaccine is expected to be given to many people in a short period of time.
For this reason, the CDC has developed an app for smartphones called "V-Safe" to investigate side reactions and confirm the effectiveness of the vaccine so that the inoculated person can report their health condition. ..
If you want to know more
▼ CDC = Centers for Disease Control and Prevention Report (Morbidity and Mortality Weekly Report / MMWR) January 6, 2021 https://www.cdc.gov/mmwr/volumes/70/wr/pdfs/mm7002e1-H.pdf
▼ CDC Press Briefing (Remarks) January 6, 2021 https://www.cdc.gov/media/releases/2021/t0106-cdc-update-covid-19.html
▼ CDC's cautionary call regarding allergic reactions ( Last updated December 31, 2020)
Vaccine Rice causes severe allergic reaction in 21 out of 1.9 million people
The US CDC = Centers for Disease Control and Prevention released a report on January 6 that 21 out of about 1.9 million people vaccinated with the new coronavirus had a severe allergic reaction called anaphylaxis. Did.
All those who could be tracked have already recovered, and CDC executives say, "Anaphylaxis is rare, but we will continue to investigate."
According to the report, about 1.9 million people have been vaccinated nationwide by the 23rd of last month, with 62% female and 34% male, and the rest unknown, according to the report. did.
Of these, 4393 reports, including those not known to be related to vaccines, were 0.2%.
In addition, 21 people showed symptoms of anaphylaxis, which is a severe allergic reaction, and 17 of them had allergic reactions in the past due to drugs or food.
The median age of those who show symptoms is 40 years, 90% are women, and the time until symptoms appear is from 2 minutes to 2.5 hours, but 70% is within 15 minutes after inoculation, and the subsequent course is The 20 people we were able to track down are all already recovering.
A CDC executive said, "Anaphylaxis due to the new coronavirus vaccine is rare, but we will continue to follow up on its safety." In addition to observing health for a certain period of time after vaccination and preparing for severe allergic reactions, It is important to warn people who are allergic to the components of the vaccine not to get vaccinated.