Created by researchers at the University of California, Irvine

New chip to help diagnose and treat cancer

Heterogeneity at the cellular level within carcinoid tumors can lead to treatment resistance.

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Researchers at the University of California, Irvine, in the United States, have created a new bioelectronic chip to study the problem of heterogeneity of cancer cells, with the aim of reducing their ability to resist various therapeutic methods.

The scientific journal “Advanced Biosystems” reported that the team of researchers in the fields of electrical engineering, computer science and biomedicine at the university developed the new chip through artificial intelligence sciences, fluid and nanoparticle research, and manufactured it using stereoscopic printing techniques, so that it could be used in examining various cancerous tumors and distinguishing between them and Healthy tissues at the cellular level inside the body.

The website Science Daily, a technology specialist, quoted by researcher Kushal Joshi, a specialist in the field of biomedical engineering, as saying that "heterogeneity at the cellular level within tumors can lead to resistance to treatment methods, to varying degrees according to each patient." The new technology enables the possibility of treating this problem by accurately classifying cancer cells within a single sample.

The study team emphasized that «the analysis of cancer cells is of great importance to determine the types of cancer for each patient, as well as the study of cellular heterogeneity, and allows the possibility of knowing the development of cancer, and providing more efficient treatment methods».

The research team created a device to test the prototype of the new chip, as the samples of cells to be studied are placed inside channels containing certain liquids, with electrodes installed to monitor the electrical properties of the diseased cells compared to the healthy cells of the patient, and then analyze them by the electronic chip.

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