Keio University clinical research aiming at functional recovery of heart disease patients using iPS cells Approval August 27, 19:41
A clinical study of Keio University, which aims to recover function by transplanting heart muscle cells made from iPS cells to patients with severe heart disease, was approved by the national subcommittee. The clinical research aiming at the recovery of heart function using iPS cells is being conducted by a group of Osaka University, and will follow.
At a meeting of the Ministry of Health, Labor and Welfare held on the 27th, a group of professor Keiichi Fukuda of the Keio University School of Medicine planned a heavy heart called "dilated cardiomyopathy", a cell of the heart muscle made from iPS cells. A clinical study was approved for transplantation in patients with the disease.
“Dilated cardiomyopathy” is a disease in which the heart's ability to pump blood is weakened, and in severe cases, heart transplantation is also performed. In a clinical study, 3 patients with heart muscle cells made from iPS cells 5000 Tens of millions will be transplanted, and the safety will be confirmed over a year, and the efficacy will be examined.
The subcommittee discussed the appropriateness of the criteria for selecting target patients, and accepted that clinical studies should be conducted assuming that there are no problems.
A clinical study aimed at recovering the function of the heart using iPS cells was carried out directly by the group of Osaka University by culturing heart muscle cells in a sheet form in January this year. Keio University's clinical research will be followed by an operation to paste.
Professor Fukuda says, "I want to deliver to the patient as soon as possible, but I want to carefully check the steps and proceed with the first transplant surgery by the end of this fiscal year."