Connie Caleb, the first American who underwent a face transplant, died at the age of 57 after nearly twelve years after surgery, what was announced yesterday by a Cleveland hospital that was caring for her.
Caleb had major facial deformities due to a bullet fired by her husband who was trying to kill him before he directed the weapon in 2004. In 2008, she underwent a complicated transplant operation that affected 80 percent of her face and lasted 22 hours.
"We are saddened by the loss of Caleb, the first person who underwent a face transplant in the United States. It has been an inspiration to all of us at the hospital," Cleveland Clinic, northern Ohio, wrote on Twitter.
Doctor Frank Papai, the superintendent of the department of dermatology and plastic surgery at the hospital, said in a statement that Caleb became the person who lived the longest period after undergoing a face transplant.
The world's first face transplant occurred on November 27, 2005 in France, and Isabelle Dinoire underwent a deformation of her face due to an attack by her dog. She died in April 2016 after returning to a rare malignant tumor.
On April 13, 2006, two-thirds of the face was transplanted to a farmer in China who had been attacked by a bear. He died in July 2008 after he stopped taking medications intended for patients who underwent transplants and chose to treat traditional herbs.

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