Future vaccination campaigns against Covid-19, when a safe and effective vaccine will be available in France, will have to target as a priority healthcare staff and people at risk, recommended this Tuesday the High Authority of Health (HAS).
"Whatever the epidemic situation when a vaccine arrives, front-line health and medico-social professionals appear to be the priority and essential target populations", indicates the HAS in a press release accompanying the dissemination of recommendations on the vaccine strategy to be adopted. In addition, the HAS considers "that people at risk of severe forms of Covid-19 (people over 65 years of age, people with comorbidity) will also be priority targets (of vaccination campaigns) as soon as clinical trials will ensure a favorable risk / benefit. "
Several scenarios depending on the contamination
For this first work of recommendations on future vaccination campaigns, the HAS retained four scenarios according to the level of circulation of the virus upon arrival of the vaccines: strong viral circulation at the national level, strong localized circulation in certain territories, viral circulation at national level. low noise (limited foci of infection), no indicator of viral circulation.
“Each of these situations implies different choices on the populations to be targeted as a priority (age, state of health, profession, necessary doses, etc.) and appropriate implementation methods (professionals mobilized to vaccinate, follow-up of vaccinated people, conditions of 'administration and storage)', explains the authority. The characteristics of the vaccines available will also influence the choice of vaccine strategy, specifies the independent authority which had been approached by the Ministry of Health to formulate "preliminary recommendations" on the vaccine strategy. They will be updated according to the evaluation of the vaccines which will obtain a marketing authorization and the indications formulated by the health authorities.
Many vaccines still in testing
The HAS also plans, depending on the vaccines and the quantity of doses available, to refer the matter to the National Ethics Council "on ethical issues related to the prioritization of populations to be vaccinated". The search for a vaccine against Covid-19 is the subject of a frantic planetary race. In its latest update dated July 24, the WHO (World Health Organization) lists 25 “vaccine candidates” evaluated in clinical trials on humans, and 139 projects in the pre-clinical phase.
According to the European Medicines Agency (EMA), "it could take at least until early 2021 for a Covid-19 vaccine to be ready for approval and available in sufficient quantities" for global use.
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