Database of genetic information of bacteria and viruses in the intestine World's first July 11, 4:33
For the first time in the world, groups such as Osaka City University and the University of Tokyo have put together a database of genetic information on various bacteria and viruses in the intestine that have a great influence on the human intestinal environment.
The research was conducted by groups such as Professor Satoshi Uematsu of the Graduate School of Medicine, Osaka City University and the Institute of Medical Science, University of Tokyo.
There are many bacteria and viruses that infect these bacteria in the human intestine, and it is known that when the environment deteriorates, such as when too many specific bacteria increase, the disease is caused.
The group collected intestinal bacteria and viruses from 101 healthy Japanese people and analyzed all the genetic information using a supercomputer to find out which intestinal bacteria were infected with which virus.
As a result, we were able to create the world's first database of detailed genetic information on 600 types of intestinal bacteria and at least 450 types of viruses.
In addition, the group used a database to find a virus that infects and destroys enteritis-causing bacteria, and confirmed that administration of the protein made by this virus to mice with severe enteritis significantly increased the survival rate. about it.
Professor Uematsu, who conducted the research, said, "Intestinal bacteria and viruses have a huge impact on health. Using the database, we can quickly examine new treatment methods using enteric viruses." I hope it will be."