Discovery of a chemical substance that prevents resistant bacteria that are hard to respond to drugs Nagoya University June 27, 5:07
A research group at Nagoya University discovered a chemical substance that stops the action of resistant bacteria that are hard to work with, even the last trump card when treating bacterial infections. The number of cases of death due to pneumonia caused by resistant bacteria is increasing all over the world, and the research group hopes to lead to the development of new antibacterial drugs.
Resistant bacteria for which antibacterial drugs are hardly effective spread all over the world, and according to a survey by a British research institute, in the stage of 2013, 700,000 people worldwide died due to pneumonia due to resistant bacteria, and measures must be taken. For example, it is estimated that by 2050, 10 million people will die each year.
Professor Yoshiaki Arakawa's research group at Nagoya University has discovered a chemical substance that stops the action of a special protein that appears when resistant bacteria render the antibacterial drug "carbapenem" ineffective.
When this chemical is used together with "carbapenem", the growth of resistant bacteria stopped, and the effect could be confirmed even in experiments using mice.
Carbapenem has been used as the last trump card when other antibacterial drugs do not work in the medical field, but in recent years, resistant bacteria that do not work even with this antibacterial drug have spread, and have become a serious problem in countries around the world. I am.
Furthermore, the development of antibacterial drugs has been delayed for more than 20 years due to the lack of effective chemical substances, and Professor Arakawa said, ``In order to save the lives of patients, we will further improve the chemical substances and develop new antibacterial drugs. I want to connect to the development of."