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Patients with high blood pressure admitted to the hospital by Covid-19 are twice as likely to die as those without this condition, according to a study published Friday in the European Heart Journal .

"It is important for patients with hypertension to realize that they are at increased risk of death from Covid-19, " says one of the study's authors, Fei Li , a cardiologist at Xijing Hospital in Xian , central China .

Hypertensive patients who have stopped taking the treatment are even more likely to die from the new SARS-CoV-2 coronavirus once hospitalized, compared to those taking the drugs, according to this study.

For this observational study, the Chinese and Irish researchers retrospectively examined data from people admitted between February 5 and March 15 at Huoshenshan Hospital in Wuhan .

Almost 30% of those admitted, or 850 patients, suffered from hypertension. 4% of these patients died compared to 1.1% of those without this condition.

After adjusting the data to account for the difference in age, sex, and health status, the researchers calculated that the risk of dying from Covid-19 in a hospitalized hypertensive patient was twice that of others.

Stopping treatment is more dangerous

Another analysis that integrates data from this hospital and those from three other studies shows that patients taking one type of anti-hypertensive medication, the renin angiotensin system inhibitors , had a lower risk of death than those treated with other medications.

But the authors ask for caution on this point. "We suggest that patients do not interrupt or modify the usual treatment for hypertension unless their doctor requests it," explains another study author, Ling Tao , of Xijing Hospital.

The authors insist that these studies are purely observational, not based on clinical trials, and that research will need to be done to make definitive clinical recommendations.

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