Alzheimer's disease iPS cell discovery drug tested in patients Clinical trial June 5, 6:05
A group such as Kyoto University announced that they will start a clinical trial to confirm the safety and efficacy by actually administering the drug found in the experiment with iPS cells made from cells of patients with Alzheimer's disease to patients.
This was announced on the 4th by Prof. Haruhisa Inoue's group at the Institute for iPS Cell Research, Kyoto University.
According to this, in clinical trials, 7 medical institutions such as Kyoto University Hospital called "bromocriptine", which is used for treatment of Parkinson's disease, etc. for patients with "Family Alzheimer's disease" that is caused by genetic factors. Administer the drug
"Bromocriptine" is a drug that was found in an experiment using iPS cells made from cells provided by a patient with Alzheimer's disease. In the experiment, it has the effect of reducing abnormal proteins that accumulate in the patient's brain. This means that the cells of patients with "sexual Alzheimer's disease" were highly effective.
Over the next year or so, the group will confirm the safety and efficacy by comparing the patients who received the drug to a total of 10 patients and the patients who received the fake drug, and confirmed the safety and efficacy of “Family Alzheimer's disease”. It aims to be approved as a therapeutic drug for.
Professor Inoue said, “Familial Alzheimer's disease is a severe disease that occurs in young people who are said to have thousands of patients in Japan and play an important role in society and their families. I want it to arrive."