Can healthy people inject "extra free plasma" to prevent new crown virus? rumor

Rumor: Injectable "extra-free plasma" in healthy people can prevent new crown virus infection.

Dispelling rumors: Some researchers have detected high titer virus neutralizing antibodies in neonatal patients with neo-coronary pneumonia, which can kill new coronaviruses in vitro. Therefore, many people think that they have found a "big killer" to deal with new coronary pneumonia, and even say that healthy people can inject "extra-free plasma" to prevent new crown virus infection-this is actually a misunderstanding and understanding of plasma therapy.

"Exclusive plasma" therapy is an unconventional treatment method for severe and critically ill patients in the absence of vaccines and specific drugs in the event of a sudden major infectious disease outbreak. In this battle against neo-coronary pneumonia, the National Health Commission also clearly limited the clinical application of plasma therapy to "severe and critically ill patients" in the "Diagnosis and Treatment Plan for New Coronavirus Infected Pneumonia".

"Exclusive plasma" has a therapeutic effect on some critically ill patients, which does not mean that it can be used for the prevention of healthy people, just as we cannot use anti-venom serum to prevent snake bite. The new crown virus is mainly transmitted by the respiratory tract. The prevention of infection requires antiviral neutralizing antibodies to be deployed on the respiratory mucosa to prevent the virus from binding to the viral receptors on the surface of target cells. There is currently no evidence that "exclusive plasma" can complete this type of defense . The “extra free plasma” input from patients with new crown pneumonia is a whole plasma component from “others”. In addition to the neutralizing antibodies against the new crown virus, other antibodies, cytokines and plasma proteins that we do n’t want are also imported. It may damage the body's immune balance, induce allergic reactions, and even side effects such as "inflammatory storms" and autoimmune diseases. In addition, "exclusive plasma" comes from patients in rehabilitation, the supply is relatively inadequate, and the processing process is complicated, and the cost is high. One of the reasons for the rescue of critically ill and critically ill patients. For the mild patients, other safer methods are mainly recommended for treatment, and the most important thing for healthy people is to take protective measures to block the transmission route.