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Knee cartilage regeneration with iPS cells Clinical research Approved by national committee

2020-01-24T08:04:09.378Z

A clinical study of Kyoto University, which transplants cartilage tissue produced from iPS cells into a patient with injured knee joint cartilage, has been approved by a national committee…



Knee cartilage regeneration with iPS cells Clinical research Approved by the national committee Jan 24 16:53

The Kyoto University clinical study approved the transplantation of cartilage tissue made from iPS cells into patients with injured knee joint cartilage. This is the seventh study plan to use iPS cells for transplantation into an actual patient.

At the meeting of the Ministry of Health, Labor and Welfare held on March 24, a clinical study planned by a group of Professor Noriyuki Tsumaki and others at the iPS Cell Research Institute, Kyoto University was approved.

In the plan, cartilage tissue produced from human iPS cells will be transplanted into four patients whose cartilage of the knee joint has been damaged in sports or accidents, and safety will be confirmed over a year, and the efficacy will be examined. about it.

The subcommittee deliberated whether the research is ready to conduct the research, and whether the patient's document describing the procedure of the operation clearly describes the risk of transplanted cells becoming tumorous, etc. Approved the conduct of clinical research.

The cartilage tissue in the knee joint is scarcely regenerated even if it is injured.Currently, cartilage tissue is removed from another joint by surgery and transplanted, but the burden on the patient is an issue. Therefore, the realization of regenerative medicine using iPS cells is expected to reduce the burden on patients.

This is the seventh study plan to use iPS cells for transplantation into an actual patient, following eye diseases, heart disease and Parkinson's disease.

Source: nhk

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