A double meeting applies in the last qualifying step to Europe's premier football tournament for club teams and Juventus has everything in their own hands before the return at home next Thursday.
Lina Hurtig scored the 2-0 goal before the break.
The 25-year-old national team striker reached the top of a corner in the 44th minute and nodded through an opponent into the goal.
Before that, the Italian Cristiana Girelli put 1-0 in the twelfth minute.
Midfielder Linda Sembrant is still training to recover from her knee injury and the new acquisition Amanda Nildén started on the bench but was replaced with eleven minutes left.
Rebecka Blomqvist's Wolfsburg also has one foot in the CL group game after a 3-2 victory in the first qualifier against French Bordeaux.
Julia Molin and her Glasgow City also have good opportunities to get to the group stage.
The Swedish left-back played from the start when Glasgow managed 1-1 away against Swiss Servette.
The return will be played in Glasgow next Wednesday.