The meeting took place in Milan and ended with a score of 3: 1.
As part of the Nerazzurri, Romelu Lukaku scored a double in the 22nd and 45th minutes (the first goal was from the penalty spot), and Lautaro Martinez scored once in the 64th minute.
The only goal for the guests was scored by Gonzalo Escalante in the 61st minute.
Thus, the Romans suffered their first defeat in the Italian championship in seven matches.
"Inter" scored 50 points and tops the league table, "Lazio" (40) are in sixth position.
Miranchuk's earlier assist helped Atalanta defeat Cagliari in Serie A.