The meeting, held in Rostov-on-Don, ended with a score of 2: 1 in favor of the guests.
Rostov scored first.
Eldor Shomurodov scored in the ninth minute.
Maccabi responded with a goal from Nikita Rukavitsa in the 20th minute, and in the 60th minute, Mohammad Abu Fani took the Israeli team forward.
Rostov played out with ten men after midfielder Daniil Glebov received a straight red card in the 68th minute and left the field.
Thus, Maccabi will play either London's Tottenham Hotspur or Macedonian Shkendia in the qualifying playoffs.
Earlier it was reported that UEFA plans to retain the possibility of five substitutions in the European competition of the 2020/21 season