Analyzing all genetic information of 38 types of cancer in international cooperation
An international research group joined by RIKEN and others on 38 types of cancer from about 2800 patients has analyzed all genetic information and found that it has found more than 46 million gene mutations etc. . The use of data is expected to advance the mechanism of cancer and the development of new treatments.
International research groups in 37 countries, including RIKEN and the University of Tokyo, have analyzed all genetic information for 38 types of cancer, such as liver and prostate cancer, extracted from approximately 2,800 patients Was published in the British science magazine Nature.
The research group connected 10 supercomputers, such as the "SHIROKANE" at the Institute of Medical Science, the University of Tokyo, and proceeded with the analysis, finding a total of more than 46 million gene mutations and lack of genetic information. And other abnormalities were found.
In addition, only mutations and abnormalities that are known to be involved in the development and progression of cancer are found on average from four to five in one cancer.
It is hoped that the data will be made available to researchers around the world, which will lead to elucidation of the mechanism by which cancer occurs and the development of new treatments.
"It is of great significance that the world has united in large-scale research, and I hope that research in each country, such as the development of therapeutic methods, will progress," said RIKEN Hidetoshi Nakagawa, team leader.